Peculiarities of the Left Ventricle Segmental Diastolic Dysfunction and Structural and Geometrical Reconstruction in Children with a Diabetes Mellitus of the 1st Type

Aim of investigation is a study of the systolic and diastolic dysfunctions, including the segmental and global diastolic disturbances depending on the left ventricle geometrical values and the arterial pressure level in children with a diabetes mellitus of the 1st type.

Materials and Methods. 126 children with a diabetes mellitus of the 1st type are examined. 38 children are examined with a disease remoteness of up to 5 years; 69 children — of 5—10 years; 19 children — of more than 10 years. An echocardiographic examination with the restimulation index, systolic and diastolic function value calculation was made. A method of tissue visualization in the impulse and wave mode was used for assessment of a segmental diastolic dysfunction.

Results. The heart lesion in children with a diabetes mellitus of the 1st type was characterized by the left ventricle hypertrophy development according to eccentric type, accompanied by the left ventricle segmental diastolic dysfunction early appearance according to a delayed relaxation type. The arterial pressure increase, revealing at the indexed value analysis, is one of the most substantial factors, defining the cardiovascular system functioning disturbances.

Kazakova L.V., Karpovich E.I., Lukushkina E.F., Strongin L.G., Lukushkina A.Yu. Peculiarities of the Left Ventricle Segmental Diastolic Dysfunction and Structural and Geometrical Reconstruction in Children with a Diabetes Mellitus of the 1st Type. Sovremennye tehnologii v medicine 2010; (1): 65