Key words: external genital endometriosis, autoimmune thyroiditis, reproductive hormones, interleukins, T-, B-lymphocytes.
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Aim of investigation is a study of the hormonal and immunologic disturbance peculiarities in females with external genital endometriosis (EGE) combined with an autoimmune thyroiditis (AIT), accompanied by a thyroid gland function decrease.
Materials and Methods. 78 females with EGE of 20 to 41 years were investigated: the 1st group — 48 females with EGE without the thyroid gland pathology; the 2nd group — 30 females with EGE and AIT — hypothyrosis.
The generally clinical examination, laboratory investigation (detection of the immune system values, the antiphospholipid antibody spectrum, the thyroid and reproductive hormones), USI of the thyroid gland and small pelvis organs, a laparoscopy were made.
Results. It is established, that the more expressed alterations in a humoral and cellular immunity state take place at the EGE combination with a hypothyrosis, which complicates the EGE flow.