Key words: hypoxia, gamma-glutamyltransferase, cholinesterase.
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Aim of investigation is revealing of the kidney work disturbance peculiarities in newborns at the background of endured hypoxia.
Materials and Methods. 135 newborns, treating at a CICH №1 of N. Novgorod at the first week of life with endured hypoxia of a different degree of gravity, are examined. The biochemical investigations were conducted according to a certain scheme; a fermenturia degree was also studied.
Results. The trustworthy data is received that the kidney functions are disturbed at hypoxia: a filtration rate is decreased, which is expressed by a creatinin level increase in a blood serum; the tubular and glomerular apparates of kidneys suffer, which is confirmed by the gamma-glutamyltransferase and cholinesterase activity increase in urine; the disturbances in a calcium and phosphoric metabolism take place.
Conclusion. A complex of biochemical investigations for the kidney damage assessment is recommended for children endured a hypoxia.