Influence of a Low-intensive Red Light on a Functional State of the Rat Cardiovascular System and Blood at a Clinical Death Simulation

The aim of the work is to compare a low-intensive laser radiation (LILR) and a broad-band red light (BBRL) effectiveness on the undiluted blood and reduction of the body vegetative functions of rats endured a clinical death as a result of a massive hemorrhage.

Materials and Methods. A 10-minute clinical death was caused in rats with a free bloodletting from a common carotid artery, into which a heparin solution was infused (500 units/kg) for blood coagulation prophylaxis. A recording of the studied physiologic parameters in a postresuscitation period was made for 40 min. The experimental animals were divided into three groups. The autoblood of the first experimental group was undergoing a LILR effect; the second experimental group — a BBRL effect. A time of exposition was 10 min.

Conclusion. Irradiation of the reinfusing blood both with a LILR and with a BBRL causes a more effective resuscitation at an acute massive hemorrhage in rats endured a 10-minute clinical death. Moreover, a LILR greatly influences the arterial pressure (AP) reduction and erythrocyte resistance, and a BBRL — the erythrocyte number and the hemoglobin content in the animal blood.

Monich V.A., Malinovskaya S.L., Krylov V.N. Influence of a Low-intensive Red Light on a Functional State of the Rat Cardiovascular System and Blood at a Clinical Death Simulation. Sovremennye tehnologii v medicine 2011; (1): 11