Effectiveness of a Perftoran Use for the Human Sperm Hypothermal Conservation

The investigation of the lipid peroxidation (LPO) processes in human sperm has been carried out in the presence of “Perftoran” gas transport blood substitute. It was conducted in hypothermia conditions. An antioxidant effect of perftoran proves to be reliable. It is observed to inhibit the dienic and trienic conjugate accumulation to decrease a malone dialdehyde concentration and to increase a superoxidedismutase activity. A general antioxidant activity of ejaculate has been measured. It has been shown that an inhibition of the LPO process development by a temperature factor combined with a perftoran antioxidant effect as a hypothermal conservation medium component increases the whole antioxidant activity of the system.

Odintsov A.A., Kuchkov I.N., Cherkashina I.V., Potyomina T.E., Ryzhakov D.I. Effectiveness of a Perftoran Use for the Human Sperm Hypothermal Conservation. Sovremennye tehnologii v medicine 2011; (1): 47