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The Assessment of Invasive and Noninvasive Diagnostic Techniques of Helicobacter Pylori

The Assessment of Invasive and Noninvasive Diagnostic Techniques of Helicobacter Pylori

Leontyeva N.I., Stcherbakov I.T., Novikova L.I., Grachyova N.M., Khrennikov B.N., Stcherbakova E.G., Potekhin P.P.
Key words: histology, histobacterioscopy, Helpyl-test, Helic-test, “GastroPanel” test system.
2011, issue 2, page 57.

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The aim of the study is to present a comparative assessment of some invasive and noninvasive diagnostic techniques of Helicobacter pylori.

Materials and Methods. Helicobacter pylori has been diagnosed on 283 gastrobioptates obtained for diagnosis purposes in 113 patients with chronic gastroduodenitis using invasive (histology, histobacterioscopy, urease Helpyl-test) and noninvasive (respiratory Helic-test, “GastroPanel” immunoenzyme test system) techniques. Helicobacteriosis was verified by histobacterioscopy in 95.3% of cases, by Helpyl-test — in 83.6%, by Helic-test — in 63.2% and by “GastroPanel” test system — 87%. The involvement of antral part of the stomach using histological technique has been revealed in 59.7% of patients, and by “GastroPanel” test system — in 36.6%. The changes in gastric fundus have been diagnosed by histological technique in 20.5% of patients, and by “GastroPanel” test system — in 17.6%.

Conclusion. Among noninvasive techniques the most promising one is “GastroPanel” test system, and in a less degree — urease respiratory Helic-test; and from invasive techniques — Helpyl-test and histobacterioscopy. The data received can be used in quick H. pylori diagnosis, early treatment in a noninvasive form of chronic gastritis verification.

Leontyeva N.I., Stcherbakov I.T., Novikova L.I., Grachyova N.M., Khrennikov B.N., Stcherbakova E.G., Potekhin P.P. The Assessment of Invasive and Noninvasive Diagnostic Techniques of Helicobacter Pylori. Sovremennye tehnologii v medicine 2011; (2): 57


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