The Effect of Tobacco Smoke Condensate on Biological Properties of Agents of Nonspecific Pulmonary Pathology

The aim of the work is to study the effect of tobacco smoke condensate (TSC) on biological characteristics of the agents of nonspecific pulmonary pathology: S. pneumoniae, H. influenzae, K. pneumoniae.

Materials and Methods. By means of the technique developed there have been carried out subculture inoculation on solid media with five successive TSC dilutions: from 10 mg/ml (the 1st dilution) to 0.001 mg/ml (the 5th one).

Results. There has been observed a stimulating effect of the 4th dilution (0.01 mg/ml) in the form of biochemical reaction increase, increased mucus production, the increase of the size and a number of colonies by 25—29% (S. рneumoniae, H. influenzae), p<0.05 and by 12% (K. pneumoniae). Thus, in some concentrations, TSC stimulates the growth of microbial cells.

Shprykov A.S. The Effect of Tobacco Smoke Condensate on Biological Properties of Agents of Nonspecific Pulmonary Pathology. Sovremennye tehnologii v medicine 2011; (2): 152