The Effect of Ozone- and Bacteriophage Treatment on Systemic and Tissue Immunity in Patients of Chronic Inflammatory Diseases of Uterine Adnexa
The objective of the research is to study the possibilities of ozone- and bacteriophage treatment (OBPT) in correction of endotoxicosis and immunological disorders in patients of chronic inflammatory diseases of uterine adnexa (CIDUA).
Materials and Methods. There have been examined 100 patients with CIDUA, 50 of them have received OBPT, and 50 — traditional treatment. Some parameters of systemic and tissue immunity have been studied.
Results and Discussion. The analysis of dynamics of clinical and immune values against the background of the two methods of treatment has revealed that the response to provocation of inflammatory process complication by administration of saturating ozone concentration (5000 mkg/l) and Prodigiosan is the increase of intoxication, CIC, IL-6. Henceforth, the compared methods of treatment have showed significant difference. So, OBPT has caused the normalization of the changed acute-phase values, immunological parameters including local ones. The patients’ follow-up within a year has revealed lower recurrence rate of CIDUA complications after OBPT. It makes it possible to consider the method of ozone- and bacteriophage treatment to be pathogenetically reasonable component of complex treatment of chronic inflammatory diseases of uterine adnexa.
