Outcomes of Congenital Cystic Lung Malformations in Children and Their Management According to Clinical Progression

The aim of the investigation was to analyze the outcomes of congenital cystic lung malformations in children in accordance with clinical manifestations in pre- and postnatal period, and justify the management of patients.

Materials and Methods. We analyzed retrospectively 45 cases of congenital cystic lung malformations treated over a period from 2005 to 2012 in two main children hospitals in Nizhny Novgorod.

Results. Congenital cystic adenomatoid malformation (CCAM) is the most common congenital cystic lesion of the lung (60%). Nearly half children with this pathology have no respiratory signs in neonatal period, and in 22.2% cases there are no manifestations in early childhood either. Three cases were found to have spontaneous regression of CCAM. Cystic adenomatoid malformation and solitary congenital cysts have the most favorable prognosis if prenatal lung lesions are early detected and there are no associated congenital malformations. Only 13% children (28.8%) required surgical resection of cystic lung malformations. The survival rate of children with cystic lung malformations after surgery was 92.3%.

Conclusion. Favorable outcomes of pregnancies with cystic lung diseases constituted the majority (86.7%) of cases. Operative treatment is indicated if there are respiratory failure signs or recurrent respiratory infections.

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Galyagina N.А., Khaletskaya О.V. Outcomes of Congenital Cystic Lung Malformations in Children and Their Management According to Clinical Progression. Sovremennye tehnologii v medicine 2014; 6(2): 77