Today: Dec 3, 2024
RU / EN
Last update: Oct 30, 2024
Optical Coherence Tomography for Non-Invasive ex vivo Investigations in Dental Medicine — a Joint Group Experience (Review)

Optical Coherence Tomography for Non-Invasive ex vivo Investigations in Dental Medicine — a Joint Group Experience (Review)

Silvana Canjau, Carmen Todea, Meda Lavinia Negrutiu, Cosmin Sinescu, Florin Ionel Topala, Corina Marcauteanu, Adrian Manescu, Virgil-Florin Duma, Adrian Bradu, Adrian Gh. Podoleanu
Key words: dentistry; non-invasive investigations; biomedical imaging; optical coherence tomography.
2015, volume 7, issue 1, page 97.

Full text

html pdf
2424
2441

This review emphasizes the current knowledge related to optical coherence tomography (OCT) as a non-invasive diagnostic tool to perform ex vivo and showing great potential for in vivo structural imaging of features in the oral cavity. OCT technology can generate high-resolution cross-sectional and en-face images of the internal architecture of the investigated sample (2–3 mm in depth). To this goal, en-face time domain OCT (TD-OCT) and spectral domain OCT (SD-OCT) were employed. Topics included in this review refer to OCT non-destructive evaluations of: dental abfraction and attrition, material defects and micro-leakages at the tooth-filling interface, temporal-mandibular joint disc, quality of bracket bonding on dental hard tissue, prosthetic restorations and micro-leakages at prosthetic interfaces, root canals, presence or absence of apical micro-leakages, and osteo-integration of dental implants and of bone grafting materials. OCT revealed internal features of the material investigated with greater sensitivity than current diagnostic methods. We put our research in context with others’ results but the review reflects primarily our joint group experience and it presents images collected with our OCT systems only. The studies demonstrate the viability of OCT as a useful tool in dental medicine practice, as well as in research. Being completely non-invasive, OCT can be extended to soft tissue. Both TD and SD implementations prove the unique capabilities of OCT. For handheld scanning devices it is expected that the swept source principle (as one of the SD possibilities) will prevail, due to its high speed that allows for the reduction of distorting effects caused by the involuntary movements of the hand and of the patient. For high transversal resolution investigations, especially in more research oriented studies, it is expected that en-face TD-OCT will continue to coexist with SD-OCT methods, offering additionally a low cost quick provision of en-face view and compatibility with dynamic focus. Dynamic focus, that is the simultaneous adjustment of focus and coherence gate in depth is incompatible with SD-OCT methods and require repetitions of acquisitions under different focus in order to improve the transversal resolution, or more complex heads with division of the optical path in the object arm along different focus adjustments. In this respect, en-face TD-OCT provides a lower cost alternative to high transversal resolution of static samples.

We have shown that complementary studies are possible embracing OCT with more traditional methods, such as confocal microscopy and microCT. Combination of principles is expected to evolve due to their limitations when considered separately.

  1. Fujimoto J.G., Brezinski M.E. Optical coherence tomography imaging. In: Biomedical photonics handbook. Vo-Dinh T. (editor). CRC Press; 2003; p. 22–24, http://dx.doi.org/10.1201/9780203008997.ch13.
  2. Brady D.J. Optical imaging and spectroscopy. Wiley & Sons, Inc.; 2009, http://dx.doi.org/10.1002/9780470443736.
  3. Optical coherence tomography. Drexler W., Fujimoto J.G. (editors). Springer Berlin Heidelberg; 2008, http://dx.doi.org/10.1007/978-3-540-77550-8.
  4. Fercher A.F., Roth E. Ophthalmic laser interferometry. Proc. SPIE, Optical Instrumentation for Biomedical Laser Applications 1986; 0658: 48–51, http://dx.doi.org/10.1117/12.938523.
  5. Huang D., Swanson E.A., Lin C.P., Schuman J.S., Stinson W.G., Chang W., Hee M.R., Flotte T., Gregory K., Puliafito C.A., Fujimoto J.G. Optical coherence tomography. Science 1991; 254(5035): 1178–1181, http://dx.doi.org/10.1126/science.1957169.
  6. Podoleanu A.G., Dobre G.M., Webb D.J., Jackson D.A. Coherence imaging by use of a Newton rings sampling function. Opt Lett 1996; 21(21): 1789–1791, http://dx.doi.org/10.1364/ol.21.001789.
  7. Podoleanu A.G., Dobre G.M., Jackson D.A. En-face coherence imaging using galvanometer scanner modulation. Opt Lett 1998; 23(3): 147–149, http://dx.doi.org/10.1364/ol.23.000147.
  8. Podoleanu A.G., Seeger M., Dobre G.M., Webb D.J., Jackson D.A., Fitzke F.W. Transversal and longitudinal images from the retina of the living eye using low coherence reflectometry. J Biomed Opt 1998; 3(1): 12–20, http://dx.doi.org/10.1117/1.429859.
  9. Fercher A.F. Optical coherence tomography — development, principles, applications. Z Med Phys 2010; 20(4): 251–276, http://dx.doi.org/10.1016/j.zemedi.2009.11.002.
  10. Choma M.A., Sarunic M.V., Yang C., Izatt J.A. Sensitivity advantage of swept source and Fourier domain optical coherence tomography. Opt Express 2003; 11(18): 2183–2189, http://dx.doi.org/10.1364/OE.11.002183.
  11. Leitgeb R., Hitzenberger C.K., Fercher A.F. Performance of Fourier domain vs. time domain optical coherence tomography. Opt Express 2003; 11(8): 889–894, http://dx.doi.org/10.1364/oe.11.000889.
  12. Masters B.R. Three-dimensional confocal microscopy of the human optic nerve in vivo. Opt Express 1998; 3(10): 356–359, http://dx.doi.org/10.1364/oe.3.000356.
  13. Park B.H., Pierce M.C., Cense B., Yun S.-H., Mujat M., Tearney G.J., Bouma B.E., de Boer J.F. Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 μm. Opt Express 2005; 13(11): 3931–44, http://dx.doi.org/10.1364/opex.13.003931.
  14. Wang K., Ding Z., Wu T., Wang C., Meng J., Chen M., Xu L. Development of a non-uniform discrete Fourier transform based high speed spectral domain optical coherence tomography system. Opt Express 2009; 17(14): 12121–1231, http://dx.doi.org/10.1364/oe.17.012121.
  15. Gützinger E., Baumann B., Pircher M., Hitzenberger C.K. Polarization maintaining fiber based ultra-high resolution spectral domain polarization sensitive optical coherence tomography. Opt Express 2009; 17(25): 22704–22717, http://dx.doi.org/10.1364/oe.17.022704.
  16. Wang Y., Nelson J.S., Chen Z., Reiser B.J., Chuck R.S., Windeler R.S. Optimal wavelength for ultrahigh-resolution optical coherence tomography. Opt Express 2003; 11(12): 1411–1417, http://dx.doi.org/10.1364/OE.11.001411.
  17. Bradu A., Ma L., Bloor J.W., Podoleanu A.G. Dual optical coherence tomography/fluorescence microscopy for monitoring of Drosophila melanogaster larval heart. J Biophotonics 2009; 2(6–7): 380–388, http://dx.doi.org/10.1002/jbio.200910021.
  18. Chen R., Rudney J., Aparicio C., Fok A., Jones R.S. Quantifying dental biofilm growth using cross-polarization optical coherence tomography. Lett Appl Microbiol 2012; 54(6): 537–542, http://dx.doi.org/10.1111/j.1472-765X.2012.03243.x.
  19. Garcez A.S., Suzuki S.S., Ribeiro M.S., Mada E.Y., Freitas A.Z., Suzuki H. Biofilm retention by 3 methods of ligation on orthodontic brackets: a microbiologic and optical coherence tomography analysis. Am J Orthod Dentofacial Orthop 2011; 140(4): e193–e198, http://dx.doi.org/10.1016/j.ajodo.2011.04.019.
  20. Mandurah M.M., Sadr A., Bakhsh T.A., Shimada Y., Sumi Y., Tagami J. Characterization of transparent dentin in attrited teeth using optical coherence tomography. Lasers Med Sci 2014, [Epub ahead of print], http://dx.doi.org/10.1007/s10103-014-1541-4.
  21. Chew H.P., Zakian C.M., Pretty I.A., Ellwood R.P. Measuring initial enamel erosion with quantitative light-induced fluorescence and optical coherence tomography: an in vitro validation study. Caries Res 2014; 48(3): 254–262, http://dx.doi.org/10.1159/000354411.
  22. Braz A.K., de Araujo R.E., Ohulchanskyy T.Y., Shukla S., Bergey E.J., Gomes A.S.L., Prasad P.N. In situ gold nanoparticles formation: contrast agent for dental optical coherence tomography. J Biomed Opt 2012; 17(6): 066003, http://dx.doi.org/10.1117/1.JBO.17.6.066003.
  23. Hariri I., Sadr A., Shimada Y., Tagami J., Sumi Y. Effects of structural orientation of enamel and dentine on light attenuation and local refractive index: an optical coherence tomography study. J Dent 2012; 40(5): 387–396, http://dx.doi.org/10.1016/j.jdent.2012.01.017.
  24. Manesh S.K., Darling C.L., Fried D. Nondestructive assessment of dentin demineralization using polarization-sensitive optical coherence tomography after exposure to fluoride and laser irradiation. J Biomed Mater Res B Appl Biomater 2009; 90B(2): 802–812, http://dx.doi.org/10.1002/jbm.b.31349.
  25. Manesh S.K., Darling C.L., Fried D. Imaging natural and artificial demineralization on dentin surfaces with polarization sensitive optical coherence tomography. Proc. SPIE, Lasers in Dentistry XIV 2008; 6843: 68430M, http://dx.doi.org/10.1117/12.778788.
  26. Brady E., Mannocci F., Brown J., Wilson R., Patel S. A comparison of cone beam computed tomography and periapical radiography for the detection of vertical root fractures in nonendodontically treated teeth. Int Endod J 2014; 47(8): 735–746, http://dx.doi.org/10.1111/iej.12209.
  27. Shemesh H., van Soest G., Wu M.-K., Wesselink P.R. Diagnosis of vertical root fractures with optical coherence tomography. J Endod 2008; 34(6): 739–742, http://dx.doi.org/10.1016/j.joen.2008.03.013.
  28. Amaechi B.T., Podoleanu A., Higham S.M., Jackson D.A. Correlation of quantitative light-induced fluorescence and optical coherence tomography applied for detection and quantification of early dental caries. J Biomed Opt 2003; 8(4): 642–647, http://dx.doi.org/10.1117/1.1606685.
  29. Clarkson D.M. An update on optical coherence tomography in dentistry. Dent Update 2014; 41(2): 174–176, 179–180.
  30. Holtzman J.S., Ballantine J., Fontana M., Wang A., Calantog A., Benavides E., Gonzalez-Cabezas C., Chen Z., Wilder-Smith P. Assessment of early occlusal caries pre- and post-sealant application — an imaging approach. Lasers Surg Med 2014; 46(6): 499–507, http://dx.doi.org/10.1002/lsm.22249.
  31. Nakajima Y., Shimada Y., Sadr A., Wada I., Miyashin M., Takagi Y., Tagami J., Sumi Y. Detection of occlusal caries in primary teeth using swept source optical coherence tomography. J Biomed Opt 2014 Jan; 19(1): 16020, http://dx.doi.org/10.1117/1.JBO.19.1.016020.
  32. Chan K.H., Chan A.C., Fried W.A., Simon J.C., Darling C.L., Fried D. Use of 2D images of depth and integrated reflectivity to represent the severity of demineralization in cross-polarization optical coherence tomography. J Biophotonics 2013, [Epub ahead of print], http://dx.doi.org/10.1002/jbio.201300137.
  33. Gomez J., Zakian C., Salsone S., Pinto S.C.S., Taylor A., Pretty I.A., Ellwood R. In vitro performance of different methods in detecting occlusal caries lesions. J Dent 2013; 41(2): 180–186, http://dx.doi.org/10.1016/j.jdent.2012.11.003.
  34. Nakagawa H., Sadr A., Shimada Y., Tagami J., Sumi Y. Validation of swept source optical coherence tomography (SS-OCT) for the diagnosis of smooth surface caries in vitro. J Dent 2013; 41(1): 80–89, http://dx.doi.org/10.1016/j.jdent.2012.10.007.
  35. Nazari A., Sadr A., Campillo-Funollet M., Nakashima S., Shimada Y., Tagami J., Sumi Y. Effect of hydration on assessment of early enamel lesion using swept-source optical coherence tomography. J Biophotonics 2013; 6(2): 171–177, http://dx.doi.org/10.1002/jbio.201200012.
  36. de Azevedo C.S., Trung L.C.E., Simionato M.R.L., de Freitas A.Z., Matos A.B. Evaluation of caries-affected dentin with optical coherence tomography. Braz Oral Res 2011; 25(5): 407–413, http://dx.doi.org/10.1590/S1806-83242011000500006.
  37. Chen Y., Otis L., Zhu Q. Polarization memory effect in optical coherence tomography and dental imaging application. J Biomed Opt 2011; 16(8): 086005, http://dx.doi.org/10.1117/1.3606573.
  38. Kang H., Jiao J.J., Lee C., Le M.H., Darling C.L., Fried D. Nondestructive assessment of early tooth demineralization using cross-polarization optical coherence tomography. IEEE J Sel Top Quantum Electron 2010; 16(4): 870–876, http://dx.doi.org/10.1109/JSTQE.2009.2033610.
  39. Holtzman J.S., Osann K., Pharar J., Lee K., Ahn Y.C., Tucker T., Sabet S., Chen Z., Gukasyan R., Wilder-Smith P. Ability of optical coherence tomography to detect caries beneath commonly used dental sealants. Lasers Surg Med 2010; 42(8): 752–759, http://dx.doi.org/10.1002/lsm.20963.
  40. Huminicki A., Dong C., Cleghorn B., Sowa M., Hewko M., Choo-Smith L.P. Determining the effect of calculus, hypocalcification, and stain on using optical coherence tomography and polarized Raman spectroscopy for detecting white spot lesions. Int J Dent 2010; 2010: 879252, http://dx.doi.org/10.1155/2010/879252.
  41. Shimada Y., Sadr A., Burrow M.F., Tagami J., Ozawa N., Sumi Y. Validation of swept-source optical coherence tomography (SS-OCT) for the diagnosis of occlusal caries. J Dent 2010; 38(8): 655–665, http://dx.doi.org/10.1016/j.jdent.2010.05.004.
  42. Maia A.M., Fonsêca D.D., Kyotoku B.B., Gomes A.S. Characterization of enamel in primary teeth by optical coherence tomography for assessment of dental caries. Int J Paediatr Dent 2010; 20(2): 158–164, http://dx.doi.org/10.1111/j.1365-263X.2009.01025.x.
  43. Tao Y.C., Fried D. Selective removal of natural occlusal caries by coupling near-infrared imaging with a CO2 laser. Proc. SPIE, Lasers in Dentistry XIV 2008; 6843: 68430I, http://dx.doi.org/10.1117/12.778790.
  44. Jones R.S., Darling C.L., Featherstone J.D., Fried D. Imaging artificial caries on the occlusal surfaces with polarization-sensitive optical coherence tomography. Caries Res 2006; 40(2): 81–89, http://dx.doi.org/10.1159/000091052.
  45. Fried D., Xie J., Shafi S., Featherstone J.D.B., Breunig T.M., Le C. Imaging caries lesions and lesion progression with polarization sensitive optical coherence tomography. J Biomed Opt 2002; 7(4): 618–627, http://dx.doi.org/10.1117/1.1509752.
  46. Amaechi B.T., Higham S.M., Podoleanu A.G., Rogers J.A., Jackson D.A. Use of optical coherence tomography for assessment of dental caries: quantitative procedure. J Oral Rehabil 2001; 28(12): 1092–1093, http://dx.doi.org/10.1046/j.1365-2842.2001.00840.x.
  47. Colston B.W.Jr., Sathyam U.S., DaSilva L.B., Everett M.J., Stroeve P., Otis L.L. Dental OCT. Opt Express 1998; 3(6): 230–238, http://dx.doi.org/10.1364/oe.3.000230.
  48. Darling C.L., Staninec M., Chan K.H., Kang H., Fried D. Remineralization of root caries monitored using cross-polarization optical coherence tomography. Proc. SPIE, Lasers in Dentistry XVIII 2012; 8208: 82080V, http://dx.doi.org/10.1117/12.914633.
  49. Manesh S.K., Darling C.L., Fried D. Polarization-sensitive optical coherence tomography for the nondestructive assessment of the remineralization of dentin. J Biomed Opt 2009; 14(4): 044002, http://dx.doi.org/10.1117/1.3158995.
  50. Manesh S.K., Darling C.L., Fried D. Assessment of dentin remineralization with PS-OCT. Proc. SPIE, Lasers in Dentistry XV 2009; 7162: 71620W, http://dx.doi.org/10.1117/12.816865.
  51. Natsume Y., Nakashima S., Sadr A., Shimada Y., Tagami J., Sumi Y. Estimation of lesion progress in artificial root caries by swept source optical coherence tomography in comparison to transverse microradiography. J Biomed Opt 2011; 16(7): 071408, http://dx.doi.org/10.1117/1.3600448.
  52. Chong S.L., Darling C.L., Fried D. Nondestructive measurement of the inhibition of demineralization on smooth surfaces using polarization-sensitive optical coherence tomography. Lasers Surg Med 2007; 39(5): 422–427, http://dx.doi.org/10.1002/lsm.20506.
  53. Chong S.L. Detection of white spot lesions around orthodontic brackets using polarization-sensitive optical coherence tomography. Am J Orthod Dentofacial Orthop 2007; 132(5): 711, http://dx.doi.org/10.1016/j.ajodo.2007.02.032.
  54. Lee R.C., Kang H., Darling C.L., Fried D. Automated assessment of the remineralization of artificial enamel lesions with polarization-sensitive optical coherence tomography. Biomed Opt Express 2014; 5(9): 2950–2962, http://dx.doi.org/10.1364/BOE.5.002950.
  55. Mandurah M.M., Sadr A., Shimada Y., Kitasako Y., Nakashima S., Bakhsh T.A., Tagami J., Sumi Y. Monitoring remineralization of enamel subsurface lesions by optical coherence tomography. J Biomed Opt 2013; 18(4): 046006, http://dx.doi.org/10.1117/1.JBO.18.4.046006.
  56. Kang H., Darling C.L., Fried D. Nondestructive monitoring of the repair of enamel artificial lesions by an acidic remineralization model using polarization-sensitive optical coherence tomography. Dent Mater 2012; 28(5): 488–494, http://dx.doi.org/10.1016/j.dental.2011.11.020.
  57. Jones R.S., Fried D. Remineralization of enamel caries can decrease optical reflectivity. J Dent Res 2006; 85(9): 804–808, http://dx.doi.org/10.1177/154405910608500905.
  58. Benson P.E., Shah A.A., Willmot D.R. Polarized versus nonpolarized digital images for the measurement of demineralization surrounding orthodontic brackets. The Angle Orthodontist 2008; 78(2): 288–293, http://dx.doi.org/10.2319/121306-511.1.
  59. Kotaku M., Murayama R., Shimamura Y., Takahashi F., Suzuki T., Kurokawa H., Miyazaki M. Evaluation of the effects of fluoride-releasing varnish on dentin demineralization using optical coherence tomography. Dent Mater J 2014; 33(5): 648–655, http://dx.doi.org/10.4012/dmj.2014-072.
  60. Arnaud T.M.S., de Barros Neto B., Diniz F.B. Chitosan effect on dental enamel de-remineralization: an in vitro evaluation. J Dent 2010; 38(11): 848–852, http://dx.doi.org/10.1016/j.jdent.2010.06.004.
  61. Lee C., Darling C.L., Fried D. Polarization-sensitive optical coherence tomographic imaging of artificial demineralization on exposed surfaces of tooth roots. Dent Mater 2009; 25(6): 721–728, http://dx.doi.org/10.1016/j.dental.2008.11.014.
  62. Hsu D.J., Darling C.L., Lachica M.M., Fried D. Nondestructive assessment of the inhibition of enamel demineralization by CO2 laser treatment using polarization sensitive optical coherence tomography. J Biomed Opt 2008; 13(5): 054027, http://dx.doi.org/10.1117/1.2976113.
  63. Can A.M., Darling C.L., Ho C., Fried D. Non-destructive assessment of inhibition of demineralization in dental enamel irradiated by a λ=9.3-microm CO2 laser at ablative irradiation intensities with PS-OCT. Lasers Surg Med 2008; 40(5): 342–349, http://dx.doi.org/10.1002/lsm.20633.
  64. Hsu D.J., Darling C.L., Fried D. Imaging laser irradiated enamel surfaces with polarization sensitive optical coherence tomography. Proc. SPIE, Lasers in Dentistry XIV 2008; 6843: 8430N, http://dx.doi.org/10.1117/12.778789.
  65. Pande P., Shrestha S., Park J., Serafino M.J., Gimenez-Conti I., Brandon J., Cheng Y.S., Applegate B.E., Jo J.A. Automated classification of optical coherence tomo­graphy images for the diagnosis of oral malignancy in the hamster cheek pouch. J Biomed Opt 2014; 19(8): 086022, http://dx.doi.org/10.1117/1.JBO.19.8.086022.
  66. Hamdoon Z., Jerjes W., Upile T., McKenzie G., Jay A., Hopper C. Optical coherence tomography in the assessment of suspicious oral lesions: an immediate ex vivo study. Photodiagnosis Photodyn Ther 2013; 10(1): 17–27, http://dx.doi.org/10.1016/j.pdpdt.2012.07.005.
  67. Adegun O.K., Tomlins P.H., Hagi-Pavli E., Bader D.L., Fortune F. Quantitative optical coherence tomography of fluid-filled oral mucosal lesions. Lasers Med Sci 2013; 28(5): 1249–1255, http://dx.doi.org/10.1007/s10103-012-1208-y.
  68. Park K.J., Schneider H., Haak R. Assessment of interfacial defects at composite restorations by swept source optical coherence tomography. J Biomed Opt 2013; 18(7): 076018, http://dx.doi.org/10.1117/1.JBO.18.7.076018.
  69. Nazari A., Sadr A., Shimada Y., Tagami J., Sumi Y. 3D assessment of void and gap formation in flowable resin composites using optical coherence tomography. J Adhes Dent 2013; 15(3): 237–243, http://dx.doi.org/10.3290/j.jad.a28623.
  70. Shimada Y., Nakagawa H., Sadr A., Wada I., Nakajima M., Nikaido T., Otsuki M., Tagami J., Sumi Y. Noninvasive cross-sectional imaging of proximal caries using swept-source optical coherence tomography (SS-OCT) in vivo. J Biophotonics 2014; 7(7): 506–513, http://dx.doi.org/10.1002/jbio.201200210.
  71. Lammeier C., Li Y., Lunos S., Fok A., Rudney J., Jones R.S. Influence of dental resin material composition on cross-polarization-optical coherence tomography imaging. J Biomed Opt 2012; 17(10): 106002, http://dx.doi.org/10.1117/1.JBO.17.10.106002.
  72. Nazari A., Sadr A., Saghiri M.A., Campillo-Funollet M., Hamba H., Shimada Y., Tagami J., Sumi Y. Non-destructive characterization of voids in six flowable composites using swept-source optical coherence tomography. Dent Mater 2013; 29(3): 278–286, http://dx.doi.org/10.1016/j.dental.2012.11.004.
  73. Bakhsh T.A., Sadr A., Shimada Y., Mandurah M.M., Hariri I., Alsayed E.Z., Tagami J., Sumi Y. Concurrent evaluation of composite internal adaptation and bond strength in a class-I cavity. J Dent 2013; 41(1): 60–70, http://dx.doi.org/10.1016/j.jdent.2012.10.003.
  74. Shimada Y., Sadr A., Nazari A., Nakagawa H., Otsuki M., Tagami J., Sumi Y. 3D evaluation of composite resin restoration at practical training using swept-source optical coherence tomography (SS-OCT). Dent Mater J 2012; 31(3): 409–417, http://dx.doi.org/10.4012/dmj.2011-244.
  75. Monteiro G.Q.M., Montes M.A.J.R., Gomes A.S.L., Mota C.C.B.O., Campello S.L., Freitas A.Z. Marginal analysis of resin composite restorative systems using optical coherence tomography. Dent Mater 2011; 27(12): e213–e23, http://dx.doi.org/10.1016/j.dental.2011.08.400.
  76. Senawongse P., Pongprueksa P., Harnirattisai C., Sumi Y., Otsuki M., Shimada Y., Tagami J. Non-destructive assessment of cavity wall adaptation of class V composite restoration using swept-source optical coherence tomography. Dent Mater J 2011; 30(4): 517–522, http://dx.doi.org/10.4012/dmj.2011-061.
  77. Bakhsh T.A., Sadr A., Shimada Y., Tagami J., Sumi Y. Non-invasive quantification of resin-dentin interfacial gaps using optical coherence tomography: validation against confocal microscopy. Dent Mater 2011; 27(9): 915–925, http://dx.doi.org/10.1016/j.dental.2011.05.003.
  78. Ishibashi K., Ozawa N., Tagami J., Sumi Y. Swept-source optical coherence tomography as a new tool to evaluate defects of resin-based composite restorations. J Dent 2011; 39(8): 543–548, http://dx.doi.org/10.1016/j.jdent.2011.05.005.
  79. Makishi P., Shimada Y., Sadr A., Tagami J., Sumi Y. Non-destructive 3D imaging of composite restorations using optical coherence tomography: marginal adaptation of self-etch adhesives. J Dent 2011; 39(4): 316–325, http://dx.doi.org/10.1016/j.jdent.2011.01.011.
  80. Matheus T.C., Kauffman C.M., Braz A.K., Mota C.C., Gomes A.S. Fracture process characterization of fiberreinforced dental composites evaluated by optical coherence tomography, SEM and optical microscopy. Braz Dent J 2010; 21(5): 420–427, http://dx.doi.org/10.1590/S0103-64402010000500008.
  81. de Melo L.S.A., de Araujo R.E., Freitas A.Z., Zezell D., Vieira N.D., Girkin J., Hall A., Carvalho M.T., Gomes A.S.L. Evaluation of enamel dental restoration interface by optical coherence tomography. J Biomed Opt 2005; 10(6): 064027, http://dx.doi.org/10.1117/1.2141617.
  82. Braz A.K.S., Aguiar C.M., Gomes A.S.L. Evaluation of the integrity of dental sealants by optical coherence tomography. Dent Mater 2011; 27(4): e60–e64, http://dx.doi.org/10.1016/j.dental.2010.11.010.
  83. Jones R.S., Staninec M., Fried D. Imaging artificial caries under composite sealants and restorations. J Biomed Opt 2004; 9(6): 1297–1304, http://dx.doi.org/10.1117/1.1805562.
  84. Otis L.L., al-Sadhan R.I., Meiers J., Redford-Badwal D. Identification of occlusal sealants using optical coherence tomography. J Clin Dent 2003; 14(1): 7–10.
  85. Minamino T., Mine A., Omiya K., Matsumoto M., Nakatani H., Iwashita T., Ohmi M., Awazu K., Yatani H. Nondestructive observation of teeth post core space using optical coherence tomography: a pilot study. J Biomed Opt 2014; 19(4): 046004, http://dx.doi.org/10.1117/1.JBO.19.4.046004.
  86. Shemesh H., van Soest G., Wu M.-K., van der Sluis L.W.M., Wesselink P.R. The ability of optical coherence tomography to characterize the root canal walls. J Endod 2007; 33(11): 1369–1373, http://dx.doi.org/10.1016/j.joen.2007.06.022.
  87. Kikuchi K., Akiba N., Sadr A., Sumi Y., Tagami J., Minakuchi S. Evaluation of the marginal fit at implant — abutment interface by optical coherence tomography. J Biomed Opt 2014; 19(5): 055002, http://dx.doi.org/10.1117/1.JBO.19.5.055002.
  88. Bista B., Sadr A., Nazari A., Shimada Y., Sumi Y., Tagami J. Nondestructive assessment of current one-step self-etch dental adhesives using optical coherence tomography. J Biomed Opt 2013; 18(7): 76020, http://dx.doi.org/10.1117/1.JBO.18.7.076020.
  89. Drexler W., Fujimoto J.G. Optical coherence tomography. Springer Berlin Heidelberg; 2008, http://dx.doi.org/10.1007/978-3-540-77550-8.
  90. Xiang X., Sowa M.G., Iacopino A.M., Maev R.G., Hewko M.D., Man A., Liu K.-Z. An update on novel non-invasive approaches for periodontal diagnosis. J Periodontol 2010; 81(2): 186–198, http://dx.doi.org/10.1902/jop.2009.090419.
  91. Sumi Y., Ozawa N., Nagaosa S., Minakuchi S., Umemura O. Application of optical coherence tomography (OCT) to nondestructive inspection of dentures. Arch Gerontol Geriatr 2011; 53(2): 237–241, http://dx.doi.org/10.1016/j.archger.2010.11.022.
  92. Lin C.-L., Kuo W.-C., Chang Y.-H., Yu J.-J., Lin Y.-C. Examination of ceramic/enamel interfacial debonding using acoustic emission and optical coherence tomography. Dent Mater 2014; 30(8): 910–916, http://dx.doi.org/10.1016/j.dental.2014.05.023.
  93. Nakajima Y., Shimada Y., Miyashin M., Takagi Y., Tagami J., Sumi Y. Noninvasive cross-sectional imaging of incomplete crown fractures (cracks) using swept-source optical coherence tomography. Int Endod J 2012; 45(10): 933–941, http://dx.doi.org/10.1111/j.1365-2591.2012.02052.x.
  94. Turkistani A., Sadr A., Shimada Y., Nikaido T., Sumi Y., Tagami J. Sealing performance of resin cements before and after thermal cycling: evaluation by optical coherence tomography. Dent Mater 2014; 30(9): 993–1004, http://dx.doi.org/10.1016/j.dental.2014.05.010.
  95. Lin C.-L., Kuo W.-C., Yu J.-J., Huang S.-F. Examination of ceramic restorative material interfacial debonding using acoustic emission and optical coherence tomography. Dent Mater 2013; 29(4): 382–388, http://dx.doi.org/10.1016/j.dental.2012.12.003.
  96. Na J., Lee B.H., Baek J.H., Choi E.S. Optical approach for monitoring the periodontal ligament changes induced by orthodontic forces around maxillary anterior teeth of white rats. Med Biol Eng Comput 2008; 46(6): 597–603, http://dx.doi.org/10.1007/s11517-007-0300-0.
  97. Baek J.H., Na J., Lee B.H., Choi E.S., Sone W.S. Optical approach to the periodontal ligament under orthodontic tooth movement: a preliminary study with optical coherence tomography. Am J Orthod Dentofacial Orthop 2009; 135(2): 252–259, http://dx.doi.org/10.1016/j.ajodo.2007.10.037.
  98. Pithon M.M., dos Santos M.J., Andrade C.S.S., Leão Filho J.C., Braz A.K., de Araujo R.E., Tanaka O.M., Fidalgo T.K., dos Santos A.M., Maia L.C. Effectiveness of varnish with CPP–ACP in prevention of caries lesions around orthodontic brackets: an OCT evaluation. Eur J Orthod 2014, [Epub ahead of print], http://dx.doi.org/10.1093/ejo/cju031.
  99. Koprowski R., Machoy M., Woźniak K., Wróbel Z. Automatic method of analysis of OCT images in the assessment of the tooth enamel surface after orthodontic treatment with fixed braces. Biomed Eng Online 2014; 13: 48, http://dx.doi.org/10.1186/1475-925X-13-48.
  100. Isfeld D.M., Aparicio C., Jones R.S. Assessing near infrared optical properties of ceramic orthodontic brackets using cross-polarization optical coherence tomography. J Biomed Mater Res B Appl Biomater 2014; 102(3): 516–523, http://dx.doi.org/10.1002/jbm.b.33029.
  101. Leão Filho J.C.B., Braz A.K.S., de Souza T.R., de Araujo R.E., Pithon M.M., Tanaka O.M. Optical coherence tomography for debonding evaluation: an in-vitro qualitative study. Am J Orthod Dentofacial Orthop 2013; 143(1): 61–68, http://dx.doi.org/10.1016/j.ajodo.2012.08.025.
  102. Marcauteanu C., Negrutiu M., Sinescu C., Demjan E., Huges M., Bradu A., Dobre G., Podoleanu A.G. Occlusal overload investigations by noninvasive technology: fluorescence microscopy and en-face optical coherence tomography. Proc. SPIE, Optical Coherence Tomography and Coherence Techniques IV 2009; 7372: 737227, http://dx.doi.org/10.1117/12.831797.
  103. Mărcăuteanu C., Negrutiu M., Sinescu C., Demjan E., Huges M., Bradu A., Dobre G., Podoleanu A.G. Early detection of tooth wear by en-face optical coherence tomography. Proc. SPIE, Lasers in Dentistry XV 2009; 7162: 716205, http://dx.doi.org/10.1117/12.809828.
  104. Demjan E., Mărcăuţeanu C., Bratu D., Sinescu C., Negruţiu M., Ionita C., Topală F., Hughes M., Bradu A., Dobre G., Podoleanu A.G. Analysis of dental abfractions by optical coherence tomography. Proc. SPIE, Lasers in Dentistry XVI 2010; 7549: 754903, http://dx.doi.org/10.1117/12.842819.
  105. The Academy of Prosthodontics. The glossary of prosthodontic terms. 8th ed. St. Louis; 2005.
  106. Smith B.G., Knight J.K. An index for measuring the wear of teeth. Br Dent J 1984; 156(12): 435–438, http://dx.doi.org/10.1038/sj.bdj.4805394.
  107. Mărcăuţeanu C., Topală F., Negrutiu M.L., Stoica E.T., Sinescu C. 3D finite element analysis of restorative materials used in dental abfractions. Solid State Phenomena 2012; 188: 82–86, http://dx.doi.org/10.4028/www.scientific.net/ssp.188.82.
  108. Marcauteanu C., Negrutiu M., Sinescu C., Stoica E.T., Ionita C., Topala F., Vasile L., Bradu A., Dobre G., Podoleanu A.G. Early characterization of occlusal overloaded cervical dental hard tissues by en face optical coherence tomography. Proc. SPIE, Optical Coherence Tomography and Coherence Techniques V 2011; 8091: 80911X, http://dx.doi.org/10.1117/12.889711.
  109. Marcauteanu C., Bradu A., Sinescu C., Topala F.I., Negrutiu M.L., Podoleanu A.G. Quantitative evaluation of dental abfraction and attrition using a swept-source optical coherence tomography system. J Biomed Opt 2014; 19(2): 021108, http://dx.doi.org/10.1117/1.JBO.19.2.021108.
  110. Stoica E.T., Marcauteanu C., Bradu A., Sinescu C., Topala F.I., Negrutiu M.L., Duma V.F., Podoleanu A.G. Imaging of noncarious cervical lesions by means of a fast swept source optical coherence tomography system. Proc. SPIE, Fifth International Conference on Lasers in Medicine: Biotechnologies Integrated in Daily Medicine 2014; 8925: 89250Y, http://dx.doi.org/10.1117/12.2044214.
  111. Marcauteanu C., Bradu A., Sinescu C., Topala F.I., Negrutiu M.L., Duma V.F., Podoleanu A.G. The advantages of a swept source optical coherence tomography system in the evaluation of occlusal disorders. Proc. SPIE, Fifth International Conference on Lasers in Medicine: Biotechnologies Integrated in Daily Medicine 2014; 8925: 89250W, http://dx.doi.org/10.1117/12.2044198.
  112. Kleinetal T., Wieser W., Eigenwillig C.M., Biedermann B.R., Huber R. Megahertz OCT for ultrawide-field retinal imaging with a 1050 nm Fourier domain mode-locked laser. Opt Express 2011; 19(4): 3044–3062, http://dx.doi.org/10.1364/OE.19.003044.
  113. Wieser W., Biedermann B.R., Klein T., Eigenwillig C.M., Huber R. Multi-megahertz OCT: high quality 3D imaging at 20 million A-scans and 4.5 GVoxels per second. Opt Express 2010; 18(14): 14685–14704, http://dx.doi.org/10.1364/OE.18.014685.
  114. Enescu M., Sinescu C., Negrutiu M., Negru R., Marsavina L., Topala F., Rominu R., Petrescu E., Bradu A., Dobre G., Rominu M., Podoleanu A. Amalgam and composite resin interface investigation by optical coherence tomography. Advances in Communications, Computers, Systems, Circuits and Devices 2010; p. 316–322.
  115. Sinescu C., Marsavina L., Negrutiu M.L., Rusu L.C., Ardelean L., Ionita C., Podoleanu A.G., Rominu M., Topala F.I. Confocal microscopy combined with time domain optical coherence tomography and micro computer tomography in interface evaluation of class II direct composite restoration. Rev Chim 2011; 62(10): 1039–1041.
  116. Negruţiu M.L., Sinescu C., Topala F., Ionita C., Marcauteanu C., Petrescu E.L., Podoleanu A.G. Imagistic evaluation of direct dental restoration: en face OCT versus SEM and microCT. Proc. SPIE, Optical Coherence Tomography and Coherence Techniques V 2011; 8091: 80911T, http://dx.doi.org/10.1117/12.890021.
  117. Topala F., Sinescu C., Negrutiu M., Bradu A., Rominu M., Podoleanu A.G. 3D reconstructions of resin dental fillings based on en face OCT images. Advances in Biology, Bioengineering and Environment 2010; p. 19–22.
  118. Rominu M., Sinescu C., Negrutiu M.L., Rominu R.O., Pop D.M., Topala F., Stoia A., Petrescu E., Bradu A., Dobre G., Podoleanu A.G. Adhesive improvement in optical coherence tomography combined with confocal microscopy for class V cavities investigations. Proc. SPIE, Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging 2010; 7626: 76260Y, http://dx.doi.org/10.1117/12.844538.
  119. Marcauteanu C., Negrutiu M.L., Ardelean L., Rusu L.C., Podoleanu A. Evaluation of the prognosis of compomer class V restorations through en face optical coherence tomography. Rev Chim 2012; 63(5): 545–547.
  120. Sinescu C., Negrutiu M.L., Todea C., Balabuc C., Filip L., Rominu R., Bradu A., Hughes M., Podoleanu A.G. Quality assessment of dental treatments using en-face optical coherence tomography. J Biomed Opt 2008; 13(5): 054065, http://dx.doi.org/10.1117/1.2992593.
  121. He Y., Wang R.K. Dynamic optical clearing effect of tissue impregnated with hyperosmotic agents and studied with optical coherence tomography. J Biomed Opt 2004; 9(1): 200–206, http://dx.doi.org/10.1117/1.1629682.
  122. Sinescu C., Marsavina L., Negrutiu M.L., Rusu L.C., Ardelean L., Rominu M., Antoniac I., Topala F.I., Podoleanu A.G. New metallic nanoparticles modified adhesive used for time domain optical coherence tomography evaluation of class II direct composite restoration. Rev Chim 2012; 63(4): 380–383.
  123. Rominu M., Manescu A., Sinescu C., Negrutiu M.L., Topala F., Rominu R.O., Bradu A., Jackson D.A., Giuliani A., Podoleanu A.G. Zirconia enriched dental adhesive: a solution for OCT contrast enhancement. Demonstrative study by synchrotron radiation microtomography. Dent Mater 2014; 30(4): 417–423, http://dx.doi.org/10.1016/j.dental.2014.01.004.
  124. Todea C., Balabuc C., Sinescu C., Filip L., Kerezsi C., Calniceanu M., Negrutiu M., Bradu A., Hughes M., Podoleanu A.G. En face optical coherence tomography investigation of apical microleakage after laser-assisted endodontic treatment. Lasers Med Sci 2010; 25(5): 629–639, http://dx.doi.org/10.1007/s10103-009-0680-5.
  125. Todea C., Podoleanu A.G., Sinescu C., Balabuc C., Filip L., Negrutiu M. OCT investigation of apical microleakage — a preliminary in vitro study. Lasers Surg Med 2008; Suppl 20: 15.
  126. Negrutiu M.L., Sinescu C., Hughes M., Bradu A., Todea C., Balabuc C.I., Filip L.M., Podoleanu A.G. Root canal filling evaluation using optical coherence tomography. Proc. SPIE, Biophotonics: Photonic Solutions for Better Health Care 2008; 6991: 69911T, http://dx.doi.org/10.1117/12.780901.
  127. Negrutiu M.L., Nica L., Sinescu C., Topala F., Ionita C., Bradu A., Petrescu E.L., Pop D.M., Rominu M., Podoleanu A.G. SEM and microCT validation for en face OCT imagistic evaluation of endodontically treated human teeth. Proc. SPIE, Medical Imaging 2011: Physics of Medical Imaging 2011; 7961: 79614W, http://dx.doi.org/10.1117/12.878320.
  128. Negrutiu M.L., Sinescu C., Topala F., Nica L., Ionita C., Marcauteanu C., Goguta L., Bradu A., Dobre G., Rominu M., Podoleanu A.G. Root canal filling evaluation using optical coherence tomography. Proc. SPIE, Biophotonics: Photonic Solutions for Better Health Care II 2010; 7715: 77151T, http://dx.doi.org/10.1117/12.854842.
  129. Todea C., Balabuc C., Filip L., Calniceanu M., Bradu A., Highes M., Podoleanu A.G. Investigation of Er:YAG laser root canal irradiation using en-face OCT. Proc. SPIE, Optical Coherence Tomography and Coherence Techniques IV 2009; 7372: 7372_1C, http://dx.doi.org/10.1364/ECBO.2009.7372_1C.
  130. Negrutiu M., Sinescu C., Topala F., Rominu M., Markovic D., Pop D., Hughes M., Bradu A., Dobre G., Podoleanu A.G. En face optical coherence tomography investigation of interface fiber posts/adhesive cement/root canal wall. Proc. SPIE, Optical Coherence Tomography and Coherence Techniques IV 2009; 7372: 7372_1A, http://dx.doi.org/10.1364/ECBO.2009.7372_1A.
  131. Mărcăuteanu C., Demjan E., Sinescu C., Negrutiu M., Motoc A., Lighezan R., Vasile L., Hughes M., Bradu A., Dobre G., Podoleanu A.G. Preliminary optical coherence tomography investigation of the temporo-mandibular joint disc. Proc. SPIE, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV 2010; 7554: 75542G, http://dx.doi.org/10.1117/12.842783.
  132. Sinescu C., Negrutiu M.L., Huges M., Bradu A., Todea C., Rominu R., Dodenciu D., Laissue P.L., Podoleanu A.G. Investigation of bracket bonding for orthodontic treatments using en-face optical coherence tomography. Proc. SPIE, Biophotonics: Photonic Solutions for Better Health Care 2008; 6991: 69911M, http://dx.doi.org/10.1117/12.780701.
  133. Rominu R.O., Popa M., Sinescu C., Negrutiu M.L., Pop D.M., Rusu L.C., Rominu M., Topala F., Podoleanu A.G. The use of spectral domain optical coherence tomography in orthodontics. Materiale Plastice 2012; 49(2): 99–100.
  134. Rominu R., Sinescu C., Rominu M., Negrutiu M., Petrescu E., Pop D., Podoleanu A.G. The assessment of orthodontic bonding defects: optical coherence tomography followed by three-dimensional reconstruction. Proc. SPIE, Optical Complex Systems: OCS11 2011; 8172: 817214, http://dx.doi.org/10.1117/12.896772.
  135. Rominu R.O., Sinescu C., Rominu M., Negrutiu M., Laissue P., Mihali S., Cuc L., Hughes M., Bradu A., Podoleanu A. An innovative approach for investigating the ceramic bracket-enamel interface — optical coherence tomography and confocal microscopy. Proc. SPIE, 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics 2008; 7139: 71390O, http://dx.doi.org/10.1117/12.814894.
  136. Rominu R.O., Sinescu C., Pop D.M., Hughes M., Bradu A., Rominu M., Podoleanu A.G. En-face optical coherence tomography and fluorescence in evaluation of orthodontic interfaces. World Academy of Science, Engineering and Technology 2009; 3: 591–594.
  137. Demian D., Duma V.-F., Sinescu C., Negrutiu M.L., Cernat R., Topala F.I., Hutiu G., Bradu A., Podoleanu A.G. Design and testing of prototype handheld scanning probes for optical coherence tomography. Proc Inst Mech Eng H 2014; 228(8):743–753, http://dx.doi.org/10.1177/0954411914543963.
  138. Sinescu C., Negrutiu M., Tatar R., Terteleac A., Negru R., Hluscu M., Culea L., Rominu M., Marsavina L., Hughes M., Bradu A., Dobre G.M., Marcauteanu C., Demjan E., Podoleanu A.G. Investigation of osteoconductive bone substitute by particles analysis, numerical simulation and optical coherence tomography. Proc. SPIE, Lasers In Dentistry XV 2009; 7162: 716207.
  139. Negruţiu M.L., Sinescu C., Canjau S., Manescu A., Topală F.I., Hoinoiu B., Romоnu M., Mărcăuţeanu C., Duma V., Bradu A., Podoleanu A.G. Bone regeneration assessment by optical coherence tomography and MicroCT synchrotron radiation. Proc. SPIE, Optical Coherence Tomography and Coherence Techniques VI 2013; 8802: 880204, http://dx.doi.org/10.1117/12.2032624.
  140. Rusu L.C., Negrutiu M.L., Sinescu C., Hoinoiu B., Topala F.I., Duma V.F., Rominu M., Podoleanu A.G. Time domain optical coherence tomography investigation of bone matrix interface in rat femurs. Proc. SPIE, International Symposium on Photoelectronic Detection and Imaging 2013: Fiber Optic Sensors and Optical Coherence Tomography 2013; 8914: 89141H, http://dx.doi.org/10.1117/12.2036345.
  141. Sinescu C., Huges M., Bradu A., Negrutiu M., Todea C., Antonie S., Laissue P.L., Rominu M., Podoleanu A.G. Implant bone interface investigated with a non-invasive method: optical coherence tomography. Proc. SPIE, Biophotonics: Photonic Solutions for Better Health Care 2008; 6991: 69911L, http://dx.doi.org/10.1117/12.780697.
  142. Antonie S., Sinescu C., Negrutiu M., Sticlaru C., Negru R., Laissue F.L., Rominu M., Podoleanu A.G. Investigation of implant bone interface with non-invasive methods: numerical simulation, strain gauges and optical coherence tomography. Key Engineering Materials 2008; 399: 193–198, http://dx.doi.org/10.4028/www.scientific.net/KEM.399.193.
  143. Negrutiu M.L., Sinescu C., Todea C., Podoleanu A.G. Complete denture analyzed by optical coherence tomography. Proc. SPIE, Lasers in Dentistry XIV 2008; 6843: 68430R, http://dx.doi.org/10.1117/12.767106.
  144. Sinescu C., Negrutiu M., Todea C., Hughes M., Tudorache F., Podoleanu A.G. Fixed partial denture investigated by optical coherence tomography. Proc. SPIE, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII 2008; 6847: 684707, http://dx.doi.org/10.1117/12.766315.
  145. Fabricky M., Todea C., Sinescu C., Negrutiu M.L., Ardelean L., Rusu L.C., Petrescu E.L., Bratu C., Topala F.I., Podoleanu A.G., Bratu E.A. Integral ceramic inlay evaluation by time domain optical coherence tomography. Rev Chim 2012; 63(6): 633–335.
  146. Sinescu C., Negrutiu M.L., Rominu R.O., Rusu L.C., Topala F.I., Rominu M., Ardelean L., Podoleanu A. Time domain optical coherence tomography evaluation of polymeric fixed partial prostheses. Materiale Plastice 2012; 49(1): 58–61.
  147. Sinescu C., Negrutiu M., Topala F., Ionita C., Negru R., Fabriky M., Marcauteanu C., Bradu A., Dobre G., Marsavina L., Rominu M., Podoleanu A. Ceramic and polymeric dental onlays evaluated by photo elasticity, optical coherence tomography and micro computed tomography. Proc. SPIE, Optical Complex Systems: OCS11 2011; 8172: 817208, http://dx.doi.org/10.1117/12.896717.
  148. Negrutiu M.L., Sinescu C., Draganescu G., Rominu R.O., Rominu M., Rusu L.C., Ardelean L., Pop D.M., Petrescu E.L., Podoleanu A.G., Topala F.I. Laser microspectral analysis for validation of en-face OCT imagistic evaluation of microleakage between the metallic framework and veneer materials in fixed partial prostheses. Rev Chim 2011; 62(10): 1185–1188.
  149. Petrescu E., Sinescu C., Negrutiu M.L., Rominu R., Pop D.M., Rominu M. Non-invasive imagistic investigation of metal-ceramic crowns. Proc. SPIE, Optical Sensors and Biophotonics II 2011; 7990: 79900Y, http://dx.doi.org/10.1117/12.891278.
  150. Petrescu E., Sinescu C., Negrutiu M.L., Pop D., Rominu R., Enescu M., Rominu M., Bradu A., Dobre G., Podoleanu A.G. OCT and RX validation of metal-ceramic crowns repaired with ceramic material. Proc. SPIE, Optical Complex Systems: OCS11 2011; 8172: 817213, http://dx.doi.org/10.1117/12.896770.
  151. Negrutiu M.L., Sinescu C., Topala F.I., Ionita C., Goguta L., Marcauteanu C., Rominu M., Podoleanu A.G. Optical investigations of various polymeric materials used in dental technology. Proc. SPIE, Optical Complex Systems: OCS11 2011; 8172: 817216, http://dx.doi.org/10.1117/12.896932.
  152. Sinescu C., Negrutiu M.L., Ionita C., Topala F., Petrescu E., Rominu R., Pop D.M., Marsavina L., Negru R., Bradu A., Rominu M., Podoleanu A.G. Radiographic, microcomputer tomography, and optical coherence tomography investigations of ceramic interfaces. Proc. SPIE, Optical Sensors and Biophotonics II 2011; 7990: 79900W, http://dx.doi.org/10.1117/12.890272.
  153. Sinescu C., Negrutiu M.L., Ionita C., Marsavina L., Negru R., Caplescu C., Bradu A., Topala F., Rominu R.O., Petrescu E., Leretter M., Rominu M., Podoleanu A.G. Morphological characterization of dental prostheses interfaces using optical coherence tomography. Proc. SPIE, Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging 2010; 7626: 76261P, http://dx.doi.org/10.1117/12.844533.
  154. Rominu M., Sinescu C., Negrutiu M., Birtea N.M., Petrescu E., Rominu R., Hughes M., Bradu A., Dobre G., Podoleanu A.G. A qualitative approach on marginal adaptation of conditioned dental infrastructures using optical coherence tomography. Proceedings of the 1st International Conference on Manufacturing Engineering, Quality and Production Systems (Vol. I). 2009, p. 255–259.
  155. Sinescu C., Negrutiu M., Birtea N.M., Petrescu E., Rominu R.O., Marcautean C., Demjan E., Cuc L., Hughes M., Bradu A., Dobre G., Rominu M., Podoleanu A.G. Time domain and spectral optical coherence tomography investigations of integral ceramic fixed partial dentures. Proceedings of the 2nd International Conference on Maritime and Naval Science and Engineering. 2009, p. 77–81.
  156. Sinescu C., Negrutiu M., Hughes M., Bradu A., Todea C., Rominu M., Laissue P.L., Podoleanu A.G. An optical coherence tomography investigation of material defects in ceramic fixed partial dental prostheses. Proc. SPIE, Biophotonics: Photonic Solutions for Better Health Care 2008; 6991: 69910O, http://dx.doi.org/10.1117/12.780694.
  157. Negrutiu M.L., Sinescu C., Hughes M., Bradu A., Goguta L., Rominu M., Negru R., Podoleanu A.G. Fibres reinforced dentures investigated with en-face optical coherence tomography. Proc. SPIE, Biophotonics: Photonic Solutions for Better Health Care 2008; 6991: 69911U, http://dx.doi.org/10.1117/12.780904.
  158. Negrutiu M.L., Sinescu C., Hughes M., Bradu A., Rominu M., Todea C., Dobre G., Podoleanu A.G. Optical coherence tomography and confocal microscopy investigations of dental prostheses. Proc. SPIE, 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics 2008; 7139: 71390N, http://dx.doi.org/10.1117/12.816672.
  159. Sinescu C, Negruţiu M.L., Petrescu E., Rominu M., Marcauteanu C., Rominu R., Hughes M., Bradu A., Dobre G., Podoleanu A.G. Marginal adaptation of ceramic veneers investigated with en face optical coherence tomography. Proc. SPIE, Optical Coherence Tomography and Coherence Techniques IV 2009; 7372: 73722C, http://dx.doi.org/10.1117/12.831830.
  160. Duma V.-F., Lee K.-S., Meemon P., Rolland J.P. Experimental investigations of the scanning functions of galvanometer-based scanners with applications in OCT. Appl Opt 2011; 50(29): 5735–5749, http://dx.doi.org/10.1364/AO.50.005735.
  161. Duma V.-F. Optimal scanning function of a galvanometer scanner for an increased duty cycle. Opt Eng 2010; 49(10): 103001, http://dx.doi.org/10.1117/1.3497570.
  162. Lu C.D., Kraus M.F., Potsaid B., Choi W., Jayaraman V., Cable A.E., Hornegger J., Duker J.S., Fujimoto J.G. Handheld ultrahigh speed swept source optical coherence tomography instrument using a MEMS scanning mirror. Biomed Opt Express 2014; 5(1): 293–311, http://dx.doi.org/10.1364/BOE.5.000293.
  163. Jung W., Kim J., Jeon M., Chaney E.J, Stewart C.N., Boppart S.A. Handheld optical coherence tomography scanner for primary care diagnostics. IEEE Trans Biomed Eng 2011; 58(3): 741–744, http://dx.doi.org/10.1109/TBME.2010.2096816.
  164. Cernat R., Tatla T.S., Pang J., Tadrous P.J., Bradu A., Dobre G., Gelikonov G., Gelikonov V., Podoleanu A.G. Dual instrument for in vivo and ex vivo OCT imaging in an ENT department. Biomed Opt Express 2012; 3: 346–3356, http://dx.doi.org/10.1364/BOE.3.003346.
Silvana Canjau, Carmen Todea, Meda Lavinia Negrutiu, Cosmin Sinescu, Florin Ionel Topala, Corina Marcauteanu, Adrian Manescu, Virgil-Florin Duma, Adrian Bradu, Adrian Gh. Podoleanu Optical Coherence Tomography for Non-Invasive ex vivo Investigations in Dental Medicine — a Joint Group Experience (Review). Sovremennye tehnologii v medicine 2015; 7(1): 97, https://doi.org/10.17691/stm2015.7.1.13


Journal in Databases

pubmed_logo.jpg

web_of_science.jpg

scopus.jpg

crossref.jpg

ebsco.jpg

embase.jpg

ulrich.jpg

cyberleninka.jpg

e-library.jpg

lan.jpg

ajd.jpg

SCImago Journal & Country Rank