Today: Nov 21, 2024
RU / EN
Last update: Oct 30, 2024
Optimizing the Early Diagnosis of Oral Mucosal Pathologies

Optimizing the Early Diagnosis of Oral Mucosal Pathologies

Shkarednaya O.V., Goryacheva T.P., Chunikhin A.A., Bazikyan E.A., Gazhva S.I.
Key words: oral cavity; pre-cancer; cancer; early diagnosis; direct tissue autofluorescence visualization.
2017, volume 9, issue 3, page 119.

Full text

html pdf
4085
2480

The aim of the investigation was to improve the algorithm for early diagnosis of pathological and malignant processes in the oral mucosa and detection of their true boundaries by involving the method of direct tissue autofluorescence visualization in this algorithm.

Materials and Methods. There was carried out a prospective randomized clinical study whose results provided the possibility to improve the algorithm for oral mucosal examination. The scheme of topography and coding the labial mucosal elements with due account for zones of pathological process localization was developed. The limits of possibilities of direct tissue autofluorescence visualization method in verification of various oral mucosal lesions were evaluated.

Results. The proposed algorithm for examining the patients with pathological changes of the oral mucosa includes visual examination of the oral cavity and detection of pathological processes, topography and coding the mucous membrane elements, visualization and analysis of polymorphism of mucosal epithelial cells using direct tissue autofluorescence visualization method and biopsy material microscopy.

  1. Zlokachestvennye novoobrazovaniya v Rossii v 2015 godu (zabolevaemost’ i smertnost’) [Malignant neoplasms in Russia in 2015 (morbidity and mortality)]. Pod red. Kaprina A.D., Starinskogo V.V., Petrovoy G.V. [Kaprin A.D., Starinskiy V.V., Petrova G.V. (editors)]. Moscow: MNIOI im. P.A. Gertsena — filial FGBU “NMIRTs” Minzdrava Rossii, 2017; 250 p.
  2. Gazhva S.I., Grekhov A.V., Goryacheva T.P., Senina-volzhskaya I.V. Problem of early diagnosis of oral oncopathology (social aspects). Sovremennye problemy nauki i obrazovaniya 2015; 3. URL: http://science-education.ru/ru/article/view?id=19168.
  3. American Cancer Society. Cancer Facts & Figures 2013. URL: https://assets.documentcloud.org/documents/1109107/acs-facts-and-figures-2013.pdf.
  4. Mehrotra R., Gupta D.K. Exciting new advances in oral cancer diagnosis: avenues to early detection. Head Neck Oncol 2011; 3: 33, https://doi.org/10.1186/1758-3284-3-33.
  5. Gileva O.S., Libik T.V., Pozdnyakova A.A., Satyukova L.Y. Precancerous lesions in structure of oral mucosa diseases (according to medical advisory data). Problemy stomatologii 2013; 2: 3–9.
  6. Kois J.C., Truelove E. Detecting oral cancer: a new technique and case reports. Dent Today 2006; 25(10): 94–97.
  7. Poh C.F., Zhang L., Anderson D.W., Durham J.S., Williams P.M., Priddy R.W., Berean K.W., Ng S., Tseng O.L., MacAulay C., Rosin M.P. Fluorescence visualization detection of field alterations in tumor margins of oral cancer patients. Clin Cancer Res 2006; 12(22): 6716–6722, https://doi.org/10.1158/1078-0432.ccr-06-1317.
  8. Dyatel A.V. Povyshenie effektivnosti diagnostiki i lecheniya zabolevaniy krasnoy kaymy gub u patsientov s atopicheskim dermatitom. Dis. … kand. med. nauk [Enhancement of diagnostic and treatment efficiency of vermilion border in patients with atopic dermatitis. PhD Thesis]. Nizhny Novgorod; 2015.
  9. Oreshaka O.V., Dement’eva E.A. Some aspects of combination treatment of oral homogenous leukoplakia. Maestro stomatologii 2012: 1: 72–74.
Shkarednaya O.V., Goryacheva T.P., Chunikhin A.A., Bazikyan E.A., Gazhva S.I. Optimizing the Early Diagnosis of Oral Mucosal Pathologies. Sovremennye tehnologii v medicine 2017; 9(3): 119, https://doi.org/10.17691/stm2017.9.3.16


Journal in Databases

pubmed_logo.jpg

web_of_science.jpg

scopus.jpg

crossref.jpg

ebsco.jpg

embase.jpg

ulrich.jpg

cyberleninka.jpg

e-library.jpg

lan.jpg

ajd.jpg

SCImago Journal & Country Rank