Rekost-M Bone Replacement Implants Based on 3D Modeling for Closing Post-Craniotomy Skull Defects: Pre-Clinical and Clinical Studies

The aim of the study was to test an innovative implant made of the urethane bone-replacing material Rekost-M using 3D technologies for customized reconstruction of post-craniotomy skull defects.

Materials and Methods. To study the properties of the bone replacement material Rekost-M, physical, mechanical and toxicological tests, as well as preclinical studies on fibroblasts cultures and lab animals (rabbits) were carried out. Clinical evaluation of the developed implant was conducted within a multicenter trial.

Results. The replacement of post-craniotomy skull defects with implants made of the bone replacement material Rekost-M represents a reliable method of cranioplasty. Using 3D technology allows for modeling of individual implants of any complexity.

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Kolmogorov Yu.N., Uspensky I.V., Maslov A.N., Novikov A.E., Tarasov D.A., Myachin N.L., Goncharov A.Yu., Korzun A.S., Latypov T.F., Yadykov D.A., Balyazin-Parfenov I.V. Rekost-M Bone Replacement Implants Based on 3D Modeling for Closing Post-Craniotomy Skull Defects: Pre-Clinical and Clinical Studies. Sovremennye tehnologii v medicine 2018; 10(3): 95, https://doi.org/10.17691/stm2018.10.3.11