Иммунотерапия колоректального рака: современное состояние и перспективы (обзор)

Иммунотерапия солидных опухолей в настоящий момент находится в фазе интенсивного накопления новых знаний и зарождения новых многообещающих методик. Особенно перспективными видятся исследования в области поиска новых контрольных точек иммунитета, разработки высокоэффективных иммунных адъювантов на основе рекомбинантных вирусов для улучшения результатов применения противораковых вакцин, а также конструирования химерных рецепторов Т-клеток, применяющихся для адоптивной иммунотерапии. Приведены некоторые результаты клинических исследований иммунотерапевтических средств, а также экспериментальных исследований на животных моделях, которые открывают новые перспективы в лечении рака толстой кишки.

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Kit О.I., Kirichenko Е.Y., Novikova I.А., Maksimov А.Y., Filippova S.Y., Grankina А.О., Zlatnik Е.Y. Colorectal Cancer Immunotherapy: Current State and Prospects (Review). Sovremennye tehnologii v medicine 2017; 9(3): 138, https://doi.org/10.17691/stm2017.9.3.18