Новые тенденции использования терапевтической гипотермии как метода нейропротекции при повреждениях головного мозга (обзор)

В обзоре проанализированы современные клинические исследования использования терапевтической гипотермии в качестве нейропротективного метода лечения повреждений головного мозга. Этот метод демонстрирует хорошие результаты при острых повреждениях головного мозга, а также у пациентов в хронических критических состояниях. Показан интерес исследователей к изучению превентивных возможностей терапевтической гипотермии при вторичных повреждениях нейронов. Описано участие в механизмах нейропротекции головного мозга новых молекул, несущих положительные эффекты для тканей и клеток ЦНС, — белков и гормонов холодового стресса. Рассматриваются перспективы использования регулируемой целевой температуры (targeted temperature management) в лечении повреждений головного мозга.

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Usmanov E.Sh., Chubarova M.A., Saidov Sh.Kh. Emerging Trends in the Use of Therapeutic Hypothermia as a Method for Neuroprotection in Brain Damage (Review). Sovremennye tehnologii v medicine 2020; 12(5): 94, https://doi.org/10.17691/stm2020.12.5.11