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Use of a Fractional Laser Photothermolysis in Clinical Practice

Use of a Fractional Laser Photothermolysis in Clinical Practice

Karabut M.M., Gladkova N.D., Feldstein F.I., Kiselyova E.B., Fomina Yu.V., Muraev A.A.
Key words: interaction of a laser radiation with biotissues, fractional laser photothermolysis (FLPh), regeneration of tissues, skin, retina of the eye, soft tissues of a mouth cavity.
2010, issue 4, page 115.

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The stages of the laser for medical use development, the mechanisms of the laser radiation interaction with a biotissue and advantages of a laser surgery are regarded. The approaches to laser treatment of skin for a rejuvenascence and the different damage treatment are described. The principles of ablational and non-ablational laser treatment of skin and the using laser devices are regarded in detail.

A concept of a fractional laser photothermolysis (FLPh) is presented. A FLPh is directed to improvement of a biotissue regeneration and concludes in creation of the isolated untouchable thermal microwounds, surrounded by the viable tissue zones. A level of a biotissue damage and the FLPh side effects are minimal due to combination of a high effectiveness and minimum invasiveness of procedure at a conserved activation of a biotissue regeneration without a cicatrisation.

The experimental, clinical and histological data of a laser effect to skin and retina with a FLPh method is demonstrated. Two methods of fractional treatment: ablational (with a crater forming and full destruction of tissue) and non-ablational (without a tissue destruction) ones are regarded. An ablational treatment as a more aggressive and invasive one provides a more significant effect. A non-ablational treatment is the spare one and less invasive, that’s why it is more preferable if its use permits to achieve the desired result.

A correlation of the laser radiation parameters (a power, an impulse width and etc.) and the biotissue reaction for prevention of their irreversible damage is discussed. The results of experimental investigations with the effect zone maximum density detection, at which the regeneration without a cicatrisation is possible, are presented. A supposition is made, that it is possible to receive an analogous reduction reaction of the mouth cavity soft tissues on a base of the skin and retina FLPh medical use experience.

Karabut M.M., Gladkova N.D., Feldstein F.I., Kiselyova E.B., Fomina Yu.V., Muraev A.A. Use of a Fractional Laser Photothermolysis in Clinical Practice. Sovremennye tehnologii v medicine 2010; (4): 115


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