Stability of Sensory and Motor Neurons in Transection of Their Peripheral Processes in Sciatic Nerve
The aim of the investigation is to study posttraumatic survival in population of sensory (SN) and motor (MN) neurons and their size groups within 30—300 days after sciatic nerve transection in dynamics.
Materials and Methods. There was used a method of retrograde marking by fluorescent dye Mini-Ruby for quantitative detection of survival neurons in SN and MN populations forming rat’s sciatic nerve. Research materials were spinal ganglions (SG) and spinal segments (SS) L4—L6.
Conclusion. Posttraumatic death in SN and MN populations after sciatic nerve transection is asynchronous, a sensory part, as a less stable, being a leading one since subjected to earlier degeneration. The death of SN within all periods of the experiment goes before the elimination of MN, and the stabilization of sensory-motor neuron ratio occurs only on the 150th day. Later the imbalance in the relationship appears resulting in a new wave of degeneration among MN indicating incompleteness of a posttraumatic process by the 300th day. As a result, in SN population only 31.47% of nerve cells survive, and in MN population — 40.41%.
