Today: Nov 3, 2024
RU / EN
Last update: Oct 30, 2024
Experimental Justification of Enteral Lavage by Osmotically Active Solution in Acute Intestinal Obstruction Complicated by Intraabdominal Hypertension

Experimental Justification of Enteral Lavage by Osmotically Active Solution in Acute Intestinal Obstruction Complicated by Intraabdominal Hypertension

Lukoyanychev E.E., Ryabkov M.G., Kudykin M.N.
Key words: microcirculation, acute intestinal obstruction, enteral lavage, hydroxyethyl amylum.
2011, issue 2, page 146.

Full text

pdf
0
1252

The aim of the study is to determine the influence of intra-enteric pressure level on the mechanism causing decompensation of microcirculation defects in the wall of a small intestine and to assess the effectiveness of enteral lavage by hydroxyethyl amylum in case of an increased intra-enteric pressure in acute intestinal obstruction.

Materials and Methods. The experiment was carried out on 54 laboratory animals. In I series of the experiment (36 non-pedigree dogs) the processes of microcirculation in the wall of a small intestine depending on the increase level of intra-enteric pressure (5, 15, 25, 35 mm Hg) were studied. In the II series (18 rats) there was examined the effect of 10%-hydroxyethyl amylum solution on an inflammatory process in small intestine tissues when a critical level of intra-enteric pressure was adjusted.

Results. Under intra-enteric pressure in a small intestine of 15 mm Hg and more, decompensation disorders of splanchic microcirculation processes start. Under an adjusted critical level of intra-abdominal pressure, enteral lavage by 10%-hydroxyethyl amylum solution decreases the intensity of an inflammatory reaction in tissues of an intestinal wall in acute enteric obstruction.

Lukoyanychev E.E., Ryabkov M.G., Kudykin M.N. Experimental Justification of Enteral Lavage by Osmotically Active Solution in Acute Intestinal Obstruction Complicated by Intraabdominal Hypertension. Sovremennye tehnologii v medicine 2011; (2): 146


Journal in Databases

pubmed_logo.jpg

web_of_science.jpg

scopus.jpg

crossref.jpg

ebsco.jpg

embase.jpg

ulrich.jpg

cyberleninka.jpg

e-library.jpg

lan.jpg

ajd.jpg

SCImago Journal & Country Rank