The Dynamics of Pathological Processes in Patients with Prostatic Diseases, Case Management
The aim of the study is to assess the dynamics of pathological processes in prostate and suggest the management of patients with various pathological processes against the background of benign prostatic hyperplasia (BPH).
Materials and Methods. 53 patients after histologically confirmed prostatic intraepithelial neoplasias (PIN) of the 1st and the 2nd degree and BPH were reoperated, 23 of them were initially taken prostate biopsy due to cancer suspected, and 30 patients were performed diavesical adenomectomy and transurethral resection.
Conclusion. Obligate prostate precancer is PIN of the 2nd degree. 1st degree neoplasias are malignization suspected in case of the increase of prostate-specific antigen level. Chronic inflammation (prostatitis) and severe prostatic fibrosis can also be considered as precancer processes. There was suggested patients management based on the analysis of histological changes in original surgeries and reoperations.