Tension-Free Repair of Abdominal Wall Hernias Using Glue in Experiment

The use of glue compositions to attach synthetic endoprostheses (meshes) to abdominal wall tissues in tension-free repair refers to a new and prospective branch of herniology.

The aim of the investigation was to assess the capabilities of abdominal wall plasty with glue fixation of synthetic endoprostheses in experiment.

Materials and Methods. We carried out an experimental controlled study on rabbits.

The basic group (n=34) was operated using IPOM (intraperitoneal onlay mesh) technique with synthetic endoprostheses fixation by cyanoacrylate adhesive “Sulfacrylate”, with no sutures used. In the control group (n=69) there was performed IPOM plasty with mesh fixation using traditional methods — by suturing. The distribution of endoprosthesis types in the groups was comparable. The mаcroscopic changes were observed on day 14, 21, 28, 90 after the implantation.

Results. The strength of mesh fixation to the abdominal wall in both groups was sufficient: 2.625 and 2.725 scores according to a modified Vanderbilt scale, p=0.936. The intensity of adhesive process was 2.125 and 3.823 scores, respectively, p=0.009. The colon was involved in adhesive process in 6.25% of cases in the main group, in the control group — in 33.3%, p=0.049.

Conclusion. Glue fixation provides firm and reliable mesh fixation to tissues. The technique significantly decreases the intensity of adhesive process in the abdominal cavity.

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Parshikov V.V., Khodak V.А., Petrov V.V., Dvornikov А.V., Mironov А.А., Dudelson V.A., Tsybusov S.N. Tension-Free Repair of Abdominal Wall Hernias Using Glue in Experiment. Sovremennye tehnologii v medicine 2013; 5(2): 14