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Role of Iodine Deficiency in the Development of Menstrual Disorders in Young Females

Role of Iodine Deficiency in the Development of Menstrual Disorders in Young Females

Gerasimova L.I., Denisov М.S., Samoilova А.V., Gunin А.G., Denisova Т.G.
Key words: iodine deficiency disorders; menstrual disorders; iodine deficiency prevention.
2016, volume 8, issue 4, page 104.

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The aim of the investigation was to study the effect of iodine level in young females on the development of menstrual disorders.

Materials and Methods. We determined iodine content in urine by a potentiometric method using ion-selective electrodes to analyze iodide ions. Due to the high amplitude vibrations of individual iodine concentrations in urine (ioduria) to estimate the severity of iodine deficiency, we used a mean iodine concentration in urine — a median.

Results. The content of urinary iodine excretion in young females with menstrual function disorders ranged widely from 18 to 109 µg/L. The median of iodine excretion appeared to be lower than the existing standards, and was 74.8 µg/L.

We revealed the positive direct relations between ioduria and impaired menstrual function (r=0.46). To assess the effectiveness of the program of iodine deficiency prevention of menstrual function in young girls 5–6 months after iodine administration, we re-evaluated their iodine level. The number of normal findings of urinary iodine excretions was found to have increased up to 70.6% cases, neither moderate nor severe iodine deficiencies being revealed. Moreover, most young females with menstrual disorders were found to have improved functioning of the reproductive system.


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