Today: Dec 22, 2024
RU / EN
Last update: Oct 30, 2024
Modified Mitral Valve Repair with Its Insufficiency of Ischemic Genesis

Modified Mitral Valve Repair with Its Insufficiency of Ischemic Genesis

Vaykin V.E., Ryazanov M.V., Zhiltsov D.D., Zhurko S.A., Gamzaev A.B., Bolshukhin G.V., Fedorov S.A., Medvedev A.P.
Key words: ischemic mitral regurgitation; mitral valve reconstruction; coronary artery disease.
2021, volume 13, issue 2, page 59.

Full text

html pdf
2302
1478

The aim of the study was to assess the effectiveness of modified mitral valve repair in comparison with traditional methods of correcting ischemic mitral regurgitation.

Materials and Methods. The results of surgical treatment of 80 patients with coronary artery disease complicated by ischemic mitral regurgitation were analyzed. The mean age of the patients was 58.95±8.36 years; the ratio of men and women was 67:13. Heart failure of FC II (according to the NYHA classification) was detected in 6 patients (7.50%), FC III — in 69 (86.25%) patients, FC IV — in 5 (6.25%) patients.

Echocardiographic examination was used to determine the significance and genesis of mitral regurgitation in the preoperative period. 57 patients (71.25%) were detected with grade II mitral regurgitation, 23 (28.75%) had grade III.

Annuloplasty was chosen as the operation for the correction of the valve apparatus. The patients of group 1 (n=23) underwent reconstructive surgery on the mitral valve using an autopericardial strip according to the technique, which we have developed, in combination with coronary artery bypass grafting (CABG), the patients of group 2 (n=26) underwent plastic surgery using a support ring in combination with CABG, patients of group 3 (n=31) had myocardial revascularization without correction of the valve apparatus.

Results. The patients of group 2 underwent restrictive mitral annuloplasty performed with rigid support rings, group 1 — with an autopericardial strip as a soft support ring, the patients of group 3 underwent CABG alone.

One patient from group 2 died in the early postoperative period due to acute perioperative myocardial infarction.

The most common complications were pleurisy, acute cardiovascular failure, acute respiratory failure, and cardiac arrhythmias. The smallest number of complications was noted in the group 3, where patients underwent CABG alone. After surgery, all the patients showed a decrease in mitral regurgitation, which was most pronounced in the groups with annuloplasty.

When analyzing the immediate results of the operations, it was revealed that the patients of groups 1 and 2, who underwent combined interventions, had a higher percentage of complications, and the length of their stay in the ICU increased. However, these groups showed a significant improvement in mitral valve functioning. Plasty of the mitral valve with an autopericardial strip according to the technique, which we have developed, demonstrated a good hemodynamic effect, the absence of significant regurgitation in the postoperative period.

  1. Nishimura R.A., Otto C.M., Bonow R.O., Carabello B.A., Erwin J.P. III, Guyton R.A., O’Gara P.T., Ruiz C.E., Skubas N.J., Sorajja P., Sundt T.M. III, Thomas J.D.; American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2014; 63(22): 2438–2488, https://doi.org/10.1016/j.jacc.2014.02.537.
  2. Vahanian A., Alfieri O., Andreotti F., Antunes M.J., Barón-Esquivias G., Baumgartner H., Borger M.A., Carrel T.P., De Bonis M., Evangelista A., Falk V., Lung B., Lancellotti P., Pierard L., Price S., Schäfers H.J., Schuler G., Stepinska J., Swedberg K., Takkenberg J., Von Oppell U.O., Windecker S., Zamorano J.L., Zembala M.; ESC Committee for Practice Guidelines (CPG); Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC); European Association for Cardio-Thoracic Surgery (EACTS). Guidelines on the management of valvular heart disease (version 2012): the Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur J Cardiothorac Surg 2012; 42(4): S1–S44, https://doi.org/10.1093/ejcts/ezs455.
  3. Bokeriya L.A., Skopin I.I., Mironenko V.A. Khirurgicheskoe lechenie ishemicheskoy mitral’noy nedostatochnosti [Surgical treatment of ischemic mitral regurgitation]. Moscow: Izdatel’stvo NTsSSKh im. A.N. Bakuleva RAMN; 2003; p. 4–151.
  4. Carpentier A. Cardiac valve surgery: the “French correction”. J Thorac Cardiovasc Surg 1983; 86(3): 323–337.
  5. Vavilov A.V., Scopin I.I. Pathogenesis, diagnosis and surgical treatment of ischemic mitral regurgitation. Grudnaya i serdechno-sosudistaya khirurgiya 2018; 60(3): 185–192, https://doi.org/10.24022/0236-2791-2018-60-3-185-193.
  6. Timek T.A., Lai D.T., Tibayan F., Liang D., Daughters G.T., Dagum P., Zasio M.K., Lo S., Hastie T., Ingels N.B. Jr., Miller D.C. Ischemia in three left ventricular regions: insights into the pathogenesis of acute ischemic mitral regurgitation. J Thorac Cardiovasc Surg 2003; 125(3): 559–569, https://doi.org/10.1067/mtc.2003.43.
  7. Borger M.A., Murphy P.M., Alam A., Fazel S., Maganti M., Armstrong S., Rao V., David T.E. Initial results of the chordal-cutting operation for ischemic mitral regurgitation. J Thorac Cardiovasc Surg 2007; 133(6): 1483–1492, https://doi.org/10.1016/j.jtcvs.2007.01.064.
  8. Kwan J., Shiota T., Agler D.A., Popović Z.B., Qin J.X., Gillinov M.A., Stewart W.J., Cosgrove D.M., McCarthy P.M., Thomas J.D.; Real-time three-dimensional echocardiography study. Geometric differences of the mitral apparatus between ischemic and dilated cardiomyopathy with significant mitral regurgitation: real-time three-dimensional echocardiography study. Circulation 2003; 107(8): 1135–1140, https://doi.org/10.1161/01.cir.0000053558.55471.2d.
  9. Watanabe N., Ogasawara Y., Yamaura Y., Yamamoto K., Wada N., Kawamoto T., Toyota E., Akasaka T., Yoshida K. Geometric differences of the mitral valve tenting between anterior and inferior myocardial infarction with significant ischemic mitral regurgitation: quantitation by novel software system with transthoracic real-time three-dimensional echocardiography. J Am Soc Echocardiogr 2006; 19(1): 71–75, https://doi.org/10.1016/j.echo.2005.06.014.
  10. Calafiore A.M., Iacò A.L., Gallina S., Al-Amri H., Penco M., Di Mauro M. Surgical treatment of functional mitral regurgitation. Int J Cardiol 2013; 166(3): 559–571, https://doi.org/10.1016/j.ijcard.2012.05.027.
  11. Levine R.A., Schwammenthal E. Ischemic mitral regurgitation on the threshold of a solution: from paradoxes to unifying concepts. Circulation 2005; 112(2): 745–758, https://doi.org/10.1161/circulationaha.104.486720.
  12. Calafiore A.M., Gallina S., Di Mauro M., Gaeta F., Iacò A.L., D’Alessandro S., Mazzei V., Di Giammarco G. Mitral valve procedure in dilated cardiomyopathy: repair or replacement? Ann Thorac Surg 2001; 71(4): 1146–1152, https://doi.org/10.1016/s0003-4975(00)02650-3.
  13. Daimon M., Saracino G., Gillinov A.M., Koyama Y., Fukuda S., Kwan J., Song J.M., Kongsaerepong V., Agler D.A., Thomas J.D., Shiota T. Local dysfunction and asymmetrical deformation of mitral annular geometry in ischemic mitral regurgitation: a novel computerized 3D echocardiographic analysis. Echocardiography 2008; 25(4): 414–423, https://doi.org/10.1111/j.1540-8175.2007.00600.x.
  14. Acker M.A., Parides M.K., Perrault L.P., Moskowitz A.J., Gelijns A.C., Voisine P., Smith P.K., Hung J.W., Blackstone E.H., Puskas J.D., Argenziano M., Gammie J.S., Mack M., Ascheim D.D., Bagiella E., Moquete E.G., Ferguson T.B., Horvath K.A., Geller N.L., Miller M.A., Woo Y.J., D’Alessandro D.A., Ailawadi G., Dagenais F., Gardner T.J., O’Gara P.T., Michler R.E., Kron I.L.; CTSN. Mitral-valve repair versus replacement for severe ischemic mitral regurgitation. N Engl J Med 2014; 370(1): 23–32, https://doi.org/10.1056/nejmoa1312808.
  15. Magne J., Sénéchal M., Mathieu P., Dumesnil J.G., Dagenais F., Pibarot P. Restrictive annuloplasty for ischemic mitral regurgitation may induce functional mitral stenosis. J Am Coll Cardiol 2008; 51(17): 1692–1701, https://doi.org/10.1016/j.jacc.2007.11.082.
  16. De Bonis M., Lapenna E., Verzini A., La Canna G., Grimaldi A., Torracca L., Maisano F., Alfieri O. Recurrence of mitral regurgitation parallels the absence of left ventricular reverse remodeling after mitral repair in advanced dilated cardiomyopathy. Ann Thorac Surg 2008; 85(3): 932–939, https://doi.org/10.1016/j.athoracsur.2007.11.021.
  17. Spoor M.T., Geltz A., Bolling S.F. Flexible versus nonflexible mitral valve rings for congestive heart failure: differential durability of repair. Circulation 2006; 114(1Suppl): I67–I71, https://doi.org/10.1161/circulationaha.105.001453.
  18. Silberman S., Klutstein M.W., Sabag T., Oren A., Fink D., Merin O., Bitran D. Repair of ischemic mitral regurgitation: comparison between flexible and rigid annuloplasty rings. Ann Thorac Surg 2009; 87(6): 1721–1726, https://doi.org/10.1016/j.athoracsur.2009.03.066.
  19. Kareva Yu.E., Efendiev V.U., Rakhmonov S.S., Chernyavskiy A.M., Lukinov V.L. Risk factors for the return of mitral insufficiency after coronary artery bypass graft and reconstruction of the mitral valve in patients with ischemic cardiomyopathy. Patologiya krovoobrashcheniya i kardiokhirurgiya 2019; 23(2): 31–42, https://doi.org/10.21688/1681-3472-2019-2-31-42.
  20. McGee E.C., Gillinov A.M., Blackstone E.H., Rajeswaran J., Cohen G., Najam F., Shiota T., Sabik J.F., Lytle B.W., McCarthy P.M., Cosgrove D.M. Recurrent mitral regurgitation after annuloplasty for functional ischemic mitral regurgitation. J Thorac Cardiovasc Surg 2004; 128(6): 916–924, https://doi.org/10.1016/j.jtcvs.2004.07.037.
Vaykin V.E., Ryazanov M.V., Zhiltsov D.D., Zhurko S.A., Gamzaev A.B., Bolshukhin G.V., Fedorov S.A., Medvedev A.P. Modified Mitral Valve Repair with Its Insufficiency of Ischemic Genesis. Sovremennye tehnologii v medicine 2021; 13(2): 59, https://doi.org/10.17691/stm2021.13.2.07


Journal in Databases

pubmed_logo.jpg

web_of_science.jpg

scopus.jpg

crossref.jpg

ebsco.jpg

embase.jpg

ulrich.jpg

cyberleninka.jpg

e-library.jpg

lan.jpg

ajd.jpg

SCImago Journal & Country Rank