Characteristics of Left Ventricular Impaired Functional Indices in Patients with Coronary Heart Disease According to Visual Estimation and Velocity Vector Imaging
The aim of the investigation was to estimate the diagnostic capabilities of left ventricular (LV) functional indices in patients with coronary heart disease (CHD) using conventional imaging techniques (echoCG) and VVI technology.
Materials and Methods. 52 patients with CHD were examined. By visual estimation (echoCG) of LV segmental contractility all patients were divided into two groups: without LV contractile dysfunction (n=26); with segmental contractile dysfunction (n=26).
The investigation of LV function using VVI system included the study of longitudinal, radial and circular LV fibers, and the analysis of rotation indices.
Results and Discussion. VVI system helped to reveal in all patients systolic dysfunction and abnormal strain rate of LV myocardium. Patients of both groups were found to have dysfunction of longitudinal and circular fibers of LV myocardium. Decreased indices of radial fiber function were recorded in a group of patients with segmental contractility dysfunction.
Rotation function analysis was impossible in visual estimation. VVI application enabled to find disturbed rotation of basal and apical LV parts. So, the patients of both groups had decreased apical rotation indices, and 14 of them were recorded to have disturbed apical and basal rotational direction of LV.
Conclusion. The use of VVI system enables to study in more detail the characteristics of LV function in CHD patients and reveal the alteration of those indices which are not found in visual control. The detection of disturbed strain and rotational properties of LV myocardium is the most urgent problem in patients with regular contractility that makes it possible to define well the management of such patients.
- Oganov R.G., Maslennikova G.Ya. Cardiovascular epidemic can be contained by prevention effort. Profilakticheskaya meditsina 2009; 12(6): 3–7.
- Oganov R.G. Cardiovascular prevention. National recommendations. Kardiovaskulyarnaya terapiya i profilaktika 2011; Suppl. 2; 10(6).
- Quinon J. Relation between extent of dysfunctional yet viable myocardium and improvement in function after revascularization. J Cardiovasc Surg 1998; 48: 124–128.
- Sedov V.M., Mirchuk K.K., Sedlitskiy Yu.I., et al. Dyslipidoproteidemia and prognosis of coronary heart disease after bypass surgery. Vestnik hirurgii 2001; 4: 13–17.
- Bokeriya L.A., Rabotnikov V.S., Buziashvili Yu.I., Chinaliev S.K., Asymbekova E.U., Matskellishvili S.T. Ishemicheskaya bolezn’ serdtsa u bol’nykh s nizkoy sokratitel’noy sposobnost’yu miokarda levogo zheludochka (diagnostika, taktika lecheniya) [Coronary heart disease in patients with low left ventricular myocardial contractility (diagnostics, management)]. Moscow: Izd-vo NTsSSKh im. A.N. Bakuleva RAMN; 2001.
- Liebermann A.N., Weiss J.L., Jugdutt B.I., et al. Relationship of regional wall motion and thickening to the extent of myocardial infarction in the dog. Circulation 1981; 63: 739–746.
- Meza M.F., Kates M.A., Barbee R.W., et al. Combination of dobutamine and myocardial contrast echocardiography to differentiate postischemic from infracted myocardium. J Am Coll Cardiol 1997; 29(5): 274–984, http://dx.doi.org/10.1016/S0735-1097(97)00016-8.
- Lang R.M., Bierig M., Devereux R.B., et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography′s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiography 2005; 18(12): 1440–1463, http://dx.doi.org/10.1016/j.echo.2005.10.005.
- Guidelines for quantitative assessment of heart chamber structure and function. Yu.A. Vasyuk (editor). Rossiyskiy kardiologicheskiy zhurnal 2012; 3(95): 1–28.
- Vasyuk Yu.A. Funktsional’naya diagnostika v kardiologii: klinicheskaya interpretatsiya [Functional diagnostics in cardiology: clinical interpretation]. Moscow: Prakticheskaya meditsina; 2009; 312 p.
- Nikitin N.P., Kliland D.D. Application of tissue myocardial Doppler echocardiography in cardiology. Kardiologia 2002; 3: 66–79.
- Alekhin M.N. Ul’trazvukovye metody otsenki deformatsii miokarda i ikh klinicheskoe znachenie [Ultrasound estimation techniques and their clinical significance]. Moscow: Vidar-M; 2012.
- Reznik E.V., Gendlin G.E., Storozhakov G.I. Ekhokardiografiya v praktike kardiologa [Echocardiography in cardiologist`s practice]. Moscow: Praktika; 2013; 212 p.
- Chan J., Hanekom L., Wong C., et al. Differentiation of subendocardial and transmural infarction using two-dimensional strain rate imaging to assess short-axis and long-axis myocardial function. J Am Coll Cardiol 2006; 48(10): 2026–2033, http://dx.doi.org/10.1016/j.jacc.2006.07.050.
- Takeuchi M., Borden W.B., Nakai H., et al. Reduced and delayed untwising of the left ventricle in patients with hypertension and left ventricular hypertrophy: a study using two-dimensional speckle tracking imaging. Eur Heart J 2007; 28(22): 2756–2762, http://dx.doi.org/10.1093/eurheartj/ehm440.
- Gjesdal O., Hopp E., Vartdal T., et al. Global longitudinal strain measured by two-dimension speckle tracking echocardiography is closely related to myocardial infarct size in chronic ischaemic heart disease. Clin Sci (Lond) 2007; 113(6): 287–296, http://dx.doi.org/10.1042/CS20070066.
- Roes S.D., Mollema S.A., Lamb H.J., et al. Validation of echocardiographic two-dimension speckle tracking longitudinal strain imaging for viability assessment in patients with chronic ischemic left ventricular dysfunction and comparison with contrast-enhanced magnetic resonance imaging. Am J Cardiol 2009; 104(3): 312–317, http://dx.doi.org/10.1016/j.amjcard.2009.03.040.
- Becker M., Hoffmann R., Kuhl H.P., et al. Analysis of myocardial deformation based on ultrasonic pixel tracking to determine transmurality in chronic myocardial infarction. Eur Heart J 2006; 27(21): 2560–2566, http://dx.doi.org/10.1093/eurheartj/ehl288.
- Choi J.O., Cho S.W., Song Y.B., et al. Longitudinal 2D strain at rest predicts the presence of left main and three vessel coronary artery disease in patients without regional wall motion abnormality. Eur J Echocardiogr 2009; 10(5): 695–701, http://dx.doi.org/10.1093/ejechocard/jep041.
- Park Y.H., Kang S.J., Song J.K., et al. Prognostic value of longitudinal strain after primary reperfusion therapy in patients with anterior-wall acute myocardial infarction. J Am Soc Echocardiogr 2008; 21(3): 262–267, http://dx.doi.org/10.1016/j.echo.2007.08.026.
- Abate E., Georgette E., Hoogslag M. Value of three-dimension speckle tracking longitudinal strain for predicting improvement of left ventricular function after acute myocardial infarction. J Am Cardiol 2012; 110(7): 961–967, http://dx.doi.org/10.1016/j.amjcard.2012.05.023.
- Toumanidis S.T., Kaladaridou A., Bramos D., et al. Apical rotation as an early indicator of left ventricular systolic dysfunction in acute anterior myocardial infarction: experimental study. Hellenic J Cardiol 2013; 54(4): 264–272.
- Pavlyukova E.N., Karpov R.S. Left ventricular deformity, rotation and axis rotation in coronary heart disease patients with severe left ventricular dysfunction. Terapevticeskij arhiv 2012; 9: 11–16.
- Jurcut R., Pappas C.J., Masci P.G., et al. Detection of regional myocardial dysfunction in patients with acute myocardial infarction using velocity vector imaging. J Am So of Echocardiogr 2008; 21(8): 879–886, http://dx.doi.org/10.1016/j.echo.2008.02.002.
- Kim H.-D., Kim H.-K., Kim M.-K., et al. Velocity vector imaging in the measurement of left ventricular twist mechanics: head-to-head one way comparison between speckle tracking echocardiography and velocity vector imaging. J Am Soc of Echocardiogr 2009; 22(12): 1344–1352, http://dx.doi.org/10.1016/j.echo.2009.09.002.
- Blutz T., Lang C.N., van Bracht M., et al. Segment-orientated analysis of two-dimensional strain and strain rate as assessed by velocity vector imaging in patients with acute myocardial infarction. Int J Med Sci 2011; 8(2):106–113, http://dx.doi.org/10.7150/ijms.8.106.
- Tkachenko S.B., Beresten' N.F. Tkanevoe doplerovskoe issledovanie miokarda [Tissue Doppler myocardial imaging]. Moscow: Real Taym; 2006; 176 p.
- Urheim S., Edvardsen T., Torp H., et al. Myocardial strain by Doppler echocardiography. Validation of a new method to quantify regional myocardial function. Circulation 2000; 102(10): 1158–1164, http://dx.doi.org/10.1161/01.CIR.102.10.1158.
- Connolly H.M., Oh J.K. Echocardiography. In: Libby P., Bonow R.O., Mann D.L., Zipes D.P. (eds.). Braunwald’s heart disease: a textbook of cardiovascular medicine. Chapter 14; Saunders; 2008; p. 227–314.
- Vasyuk Yu.A., Alekhin M.N., Khadzegova A.B., et al. Tkanevaya doppler-ekhokardiografiya i vektornyy analiz skorosti dvizheniya miokarda v otsenke funktsional’nogo sostoyaniya serdtsa [Tissue Doppler echocardiography and vector analysis of myocardial movement rate in heart functional state assessment]. Moscow: Anakharsis; 2007.
- Alekhin M.N. Tkanevoy doppler v klinicheskoy ekhokardiografii [Tissue Doppler in clinical echocardiography]. Moscow: 2005; 112 p.
- Pislaru C., Abraham T.P., Belohalavek M. Strain and strain rate echocardiography. Curr Opin Cardiol 2002; 17(5): 443–454.
- D'hooge J., Heimdal A., Jamal F., et al. Regional strain and strain rate measurements by cardiac ultrasound: principles, implementation and limitations. Eur J Echocardiogr 2000; 1(3): 154–170, http://dx.doi.org/10.1053/euje.2000.0031.
- Heimdal A., D′hooge J., Bijnens B., et al. In vitro validation of in-plane strain rate imaging. A new ultrasound technique for evaluating regional myocardial deformation based on tissue Doppler imaging. Echocardiography 1998; 15(8–II): 40.
- Henson R.E., Song S.K., Pastorek J.S., et al. Left ventricular torsion is equal in mice and humans. Am J Physiol Heart Circ Physiol 2000; 278(4): H1117– H1123.
- Opdahl A., Helle-Valle T., Remme E.W., et al. Apical rotation by speckle tracking echocardiography: a simplified bedside index of left ventricular twist. J Am Soc Echocardiogr 2008; 21: 1121–1128, http://dx.doi.org/10.1016/j.echo.2008.06.012.
- Torrent-Guasp F., Buckberg G.D., Clemente C., et al. The structure and function of the helical heart and its buttress wrapping. I. The normal macroscopic structure of the heart. Semin Thor Cardiovasc Surg 2001; 13(4): 301–319.
- Carasso Sh., Biaggi P., et al. Velocity vector imaging: standard tissue — tracking results acquired in normals — the VVI-STRAIN study. J Am Soc Echocardiogr 2012; 25(5): 543–552, http://dx.doi.org/10.1016/j.echo.2012.01.005.
- Solomon S.D., Anavekar N., Skali H., et al. Influence of ejection fraction on cardiovascular outcomes in a broad spectrum of heart failure patients. Circulation 2005; 112(24): 3738–3744, http://dx.doi.org/10.1161/CIRCULATIONAHA.105.561423.
- Han W., Xei M.X., Wang X.F., et al. Assessment of left ventricular torsion in patients with anterior wall myocardial infarction and after revascularization using speckle tracking imaging. Chin Med J (Engl) 2008; 212(16): 1543–1548.