Structuring Characteristics of Biological Fluids of Patients with Combined Cardiovascular and Gastrointestinal Pathology

The aim of the investigation was a comparative study of the result of self- and initiated crystallization of saliva and urine in patients with an isolated ulcer disease, coronary heart disease (CHD), and the combination of both.

Materials and Methods. We studied saliva and urine samplings in 35 patients with isolated CHD, in 48 — with ulcer disease, and in 112 — with the combination of both. CHD was diagnosed based on a clinical study, as well as according to the findings of instrumental studies (ECG recording at rest and physical load, Holter ECG monitoring, echocardiography). The diagnosis of ulcer disease was verified by fibrogastroduodenoscopy; helicobacteriosis was revealed by biopsy and serologic testing. The characteristics of self- and initiated crystallization of biological substrates were assessed using a semiquantitative analysis. Normal saline was a basic substance for teziography.

Results. A combined pathology was found to have a specific character in the formation of crystallogenic properties of biological fluid facies of patients. This fact is consistent with the data indicating dysmetabolic disorders, which integrate the diseases under study and are caused by Helicobacter pylori. The findings both confirm the presence of metabolic response of the body on comorbidity and also can serve as the basis for the development of noninvasive technologies to monitor the effectiveness of Helicobacter pylori eradication.

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Simonova Zh.G., Martusevich А.К., Shubina О.I., Emanuel V.L. Structuring Characteristics of Biological Fluids of Patients with Combined Cardiovascular and Gastrointestinal Pathology. Sovremennye tehnologii v medicine 2014; 6(3): 64